CD4 (GK1.5) Antibody sc-13573 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemCD4 (GK1.5) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-13573
Antibody TypePrimary Antibodies
Reactivitymouse, rat, human
Quantity200 µg/ml
ApplicationsIP, IF, IHC(P), FCM
CloneGK1.5
FormatPurified
Conjugate/TagUnconjugated
Hostrat
ClonalityMonoclonal
TargetCD4
NCBI Full Gene NameCD4 antigen, CD4 molecule
NCBI Gene AliasesL3T4, CD4mut, T4, OKT4D, IMD79, Leu-3, Ly-4
IsotypeIgG2b

Questions and Answers

What species does this CD4 antibody work with in immunofluorescence studies?

The CD4 (GK1.5) antibody has been shown to work effectively in immunofluorescence studies with mouse, human, and rat tissues, as evidenced by its use in various publications.

Can this antibody be used in studies involving inflammatory bowel disease models?

Yes, the CD4 antibody has been utilized in studies examining immune responses in murine models of colitis, where it was employed to analyze CD4+ T cell populations in the context of immune modulation and inflammation.

Is this antibody suitable for use in cancer research, particularly in tumor microenvironments?

The CD4 antibody has been cited in research focusing on tumor microenvironments, including studies that assess the role of CD4+ T lymphocytes in various cancer models, indicating its relevance in cancer immunology.

How has this antibody been applied in the context of chronic obstructive pulmonary disease (COPD) research?

The CD4 antibody has been used in studies investigating the immune response in COPD models, where it helped quantify CD4+ T cell populations and assess their role in the inflammatory processes associated with the disease.

Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) ACSL5 programs fatty acid metabolism and mitochondrial fitness to sustain pathogenic T cells and exacerbate Sjögren's syndromeInt J Biol SciJuly 13, 2026Xinyi Ren, Junhao Yin, Xinyi Ma, Jiabao Xu, Changyu Chen, Lele He, Ruowen Zhao, Yucheng Xu, Yiping Pu, Baoli Wang, et al.Leica microscope. The following primary antibodies were used: anti-CD4 (Santa Cruz Biotechnology; Cat# sc-13573), anti-CD8 (Santa Cruz Biotechnology; Cat# sc-7970), anti-CD69 (Santa Cruz Biotechnology; Cat# sc-390889),

(2) Tegumentary Leishmaniasis Associated With Immune Reconstitution in an HIV Patient-A Case ReportParasite ImmunolMay 11, 2026Marilia Brasil Xavier, Claudia Maria de Castro Gomes, Rita Catarina Medeiros Sousa, Edna Aoba Yassui Ishikawa, Elza Baía de de Brito, Silvia Ferreira Rodrigues Müller, Lucas Dos Santos Fontes, João Augusto Gomes de Souza Monteiro de de Brito, Larissa Dos Santos Alcantara, Carlos Eduardo Pereira CorbettAntibody,Manufacturer,Catalogue number,Dilution CD4,Santa Cruz Biotechnology,sc‐13573,1:50 CD8,Santa Cruz Biotechnology,sc‐1181,1:50 CD20,DakoCytomation,IS604 (clone L26),1:50 CD68,Abcam,ab955,1:400 iNOS,Abcam,ab15323,1:200 CD163,Abcam,ab156769,1:900 IL‐10,R&D Systems

(3) HMGB1 dysregulation: a neuroimmune bridge to cognitive impairment in autoimmune thyroiditisFrontiers in ImmunologyFebruary 17, 2026Jue Wang, Gaoping Chu, Longfei Ding, Wenqing You, Bin Liu, Haibo Xueand widely used marker for microglia. (Abcam, ab178847), Hmgb1 (Abcam, ab190377), CD4 (Santa Cruz, sc-13573), IL-17A (Abcam, ab79056), CD68 (Abcam, ab53444), C3 (Proteintech, 66157-1-IG), and AQP4 (Santa Cruz,

(4) LncRNA-CTD suppresses metastasis and immune evasion by modulating snail1 and MHC-I expression in colorectal cancerJournal for immunotherapy of cancerSeptember 15, 2025Xu N, Qiu H, Sun Y, Jin H, Yan S, Zhang F, Song Y, Zheng G, Liao D, Wei X, et al.anti-NLRC5 (1:100, Affinity, China), anti-TFAP4 (1:50, Abcam, ab223771), anti-CD4 (1:50, Santa Cruz, sc13573), anti-CD8 (1:50, BOSTER, A02236-1), anti-CD20 (1:50, Thermo Fisher Scientific, PA5-16701), anti-CD56

(5) MLKL Modulates Necroptosis and Neuroinflammation in a Mouse Model of MSInflammationJuly 2, 2025Minjun Xiao, Ge Gao, Jingjing Mu, Qi Sun, Yun Zhao, Xueli Fan(Santa Cruz Biotechnology, sc-374218, Monoclonal, Mouse/IgG2aκ, China) and CD4 (Santa Cruz Biotechnology, sc-13573, Monoclonal, Rat/lgG2b, China). The sections were then incubated with goat anti-rabbit IgG Alexa Fluor

(6) ZEB1 expression in Th17 cells correlated with p-STAT3 in human apical periodontitisBMC Oral HealthFebruary 27, 2025Xiaoyue Sun, Jingwen Yang, Zijun Wang, Qing Nie, Qian Yang, Wei Zhang, Mingwen Liu, Li Wang, Lingxin Zhuagainst ZEB1 (1:500; cat. no. SAB5701068; Sigma-Aldrich), rat monoclonal CD4 antibody (1:200; cat. no. sc-13573; Santa Cruz Biotechnology), mouse monoclonal IL-17 antibody (1:200; cat. no. sc-374218; Santa Cruz Biotechnology)

(7) Negative Regulation of CPSF6 Suppresses the Warburg Effect and Angiogenesis Leading to Tumor Progression Via c-Myc Signaling Network: Potential Therapeutic Target for Liver Cancer TherapyInternational Journal of Biological SciencesJune 17, 2024Deok Yong Sim, Hyo-Jung Lee, Chi-Hoon Ahn, JiEon Park, Su-Yeon Park, Bum-Ju Kil, Bum-Sang Shim, Bonglee Kim, Sung-Hoon KimNo. sc-56; Santa Cruz, USA), Caspase3 (Cat. No. 9662; Cell Signaling Technology, USA), CD4 (Cat No. sc-13573. Santa Cruz, USA), and CD8 (Cat No. sc-1181. Santa Cruz, USA), HK2 (Cat. No. 2106, Cell Signaling Technology,

(8) Modulation of TLR4/NFκB Pathways in Autoimmune MyocarditisAntioxidants (Basel, Switzerland)July 27, 2023Interdonato L, Impellizzeri D, D'Amico R, Cordaro M, Siracusa R, D'Agostino M, Genovese T, Gugliandolo E, Crupi R, Fusco R, et al.The sections were probed with the following primary antibodies: anti-CD4 (Santa Cruz Biotechnologies, sc-13573, Dallas, TX, USA) and anti-CD68 (Santa Cruz Biotechnologies, sc-20060). The slides were then washed

(9) Lymphocyte-Related Immunomodulatory Therapy with Siponimod (BAF-312) Improves Outcomes in Mice with Acute Intracerebral HemorrhageAging and diseaseJune 1, 2023Zhang Z, Li Y, Shi J, Zhu L, Dai Y, Fu P, Liu S, Hong M, Zhang J, Wang J, et al.neutrophil maker,1:150; ab9535, Abcam), rat anti-CD3 (1:250; sc-18843, Santa Cruz), rat anti-CD4 (1:250; sc-13573, Santa Cruz), mouse-anti CD8-α (1:250; sc-7970, Santa Cruz), mouse anti-CD69 (1:250; sc-373799, Santa Cruz

(10) New Insights into the Mechanism of Ulva pertusa on Colitis in Mice: Modulation of the Pain and Immune SystemMarine drugsMay 13, 2023Ardizzone A, Mannino D, Capra AP, Repici A, Filippone A, Esposito E, Campolo M.antibodies were investigated, particularly the CD4 (1:100; Santa Cruz Biotechnology, Dallas, TX, USA; sc-13573), CD8 (1:100; Santa Cruz Biotechnology, Dallas, TX, USA; sc-1177), and CD68 (1:100; Santa Cruz Biotechnology,

(11) Protective Effect of Novel Lactobacillus plantarum KC3 Isolated from Fermented Kimchi on Gut and Respiratory DisordersMicroorganismsApril 7, 2023Park MS, Kim YJ, Shin HJ, Kwon YJ, Chu J, Lee I, Kim KH, Kim BK, Kim SH, Seo HW, et al.

(12) Double hit strategy: Removal of sialic acid from the dendritic cell surface and loading with CD44+/CD24-/low cell lysate inhibits tumor growth and metastasis by targeting breast cancer stem cellsInternational immunopharmacologyJune 1, 2022Acikgoz E, Duzagac F, Guven U, Yigitturk G, Kose T, Oktem G.

(13) Optimizing therapeutic outcomes of immune checkpoint blockade by a microbial tryptophan metaboliteJournal for immunotherapy of cancerMarch 1, 2022Renga G, Nunzi E, Pariano M, Puccetti M, Bellet MM, Pieraccini G, D'Onofrio F, Santarelli I, Stincardini C, Aversa F, et al.

(14) Particulate Matter Exposure Aggravates IL-17-Induced Eye and Nose Inflammation in an OVA/Poly(I:C) Mouse ModelAllergy, asthma & immunology researchJanuary 1, 2022Bae JS, Oh SB, Kim J, Kim H, Kim JH, Kim EH, Cho KJ, Mo JH.(LS-B4912, 1:100; LSbio, Seattle, WA, USA), IL-1β (ab9722, 1:200, Abcam), TNF-α (ab6671, 1:200; Abcam), CD4 (sc-13573, 1:200; Santa Cruz Biotechnology, Santa Cruz, CA, USA), and B220 (B cell marker,14-0452-82, 1:50, eBioscience,

(15) CXCL10-armed oncolytic adenovirus promotes tumor-infiltrating T-cell chemotaxis to enhance anti-PD-1 therapyOncoimmunologyJanuary 1, 2022Li X, Lu M, Yuan M, Ye J, Zhang W, Xu L, Wu X, Hui B, Yang Y, Wei B, et al.fluorescence microscopy (Olympus). The antibodies used here included anti-PCNA (sc-56; Santa Cruz, CA, USA), anti-CD4 (sc-13573; Santa Cruz), anti-CD8 (sc-18913; Santa Cruz), anti-granzyme B (sc-8022; Santa Cruz), and anti-IFN-γ

(16) Chronic exposure to cigarette smoke transiently worsens the disease course in a mouse model of pulmonary paracoccidioidomycosisRevista do Instituto de Medicina Tropical de Sao PauloJanuary 1, 2022Buccheri R, Duarte-Neto AN, Silva FLB, Haddad GC, Silva LBRD, Azevedo Netto R, Ledesma FL, Taborda CP, Benard G.incubated for 18h with the primary antibody at 4 °C, to detect the antigens CD4 (Santa Cruz, clone sc-13573, dilution 1:50); CD8 (Invitrogen, clone MA170041, dilution 1:50); TNF (Santa Cruz, clonesc-52746, dilution

(17) Murine Chronic Pancreatitis Model Induced by Partial Ligation of the Pancreatic Duct Encapsulates the Profile of Macrophage in Human Chronic PancreatitisFrontiers in immunologyJanuary 1, 2022Peng C, Tu G, Yu L, Wu P, Zhang X, Li Z, Li Z, Yu X.Proteintech Group, Inc (Wuhan, China). Inos (13120) was purchased from Cell Signaling Technology(Shanghai, China), CD4 (SC-13573) was purchased from Santa Cruz Biotechnology Co., Ltd (Shanghai, China). Secondary antibodies: HRP-goat

(18) NLRP3 Inflammasome Inhibitor BAY-117082 Reduces Oral Squamous Cell Carcinoma ProgressionInternational journal of molecular sciencesOctober 15, 2021Scuderi SA, Casili G, Basilotta R, Lanza M, Filippone A, Raciti G, Puliafito I, Colarossi L, Esposito E, Paterniti I.Dallas, TX, USA), anti-IL-1β (sc-32294, 1:100; Santa Cruz Biotechnology, Dallas, TX, USA), anti-CD4 (sc-13573, 1:100; Santa Cruz Biotechnology, Dallas, TX, USA), anti-CD8 (sc-1177, 1:100; Santa Cruz Biotechnology,

(19) Metabolic convergence on lipogenesis in RAS, BCR-ABL, and MYC-driven lymphoid malignanciesCancer & metabolismAugust 16, 2021Liefwalker DF, Ryan M, Wang Z, Pathak KV, Plaisier S, Shah V, Babra B, Dewson GS, Lai IK, Mosley AR, et al.for 30 min and incubated overnight at 4 °C with CD4 primary antibody (1:100, Santa Cruz, Dallas, TX # sc-13573). Next day, tissues were washed in PBS and incubated with Alexa Fluor 488 Goat anti-rat secondary (1:500,

(20) Necroptosis triggered by ROS accumulation and Ca(2+) overload, partly explains the inflammatory responses and anti-cancer effects associated with 1Hz, 100 mT ELF-MF in vivoFree radical biology & medicineJune 1, 2021Barati M, Javidi MA, Darvishi B, Shariatpanahi SP, Mesbah Moosavi ZS, Ghadirian R, Khani T, Sanati H, Simaee H, Shokrollahi Barough M, et al.

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CD4 (GK1.5) Antibody

CD4 (GK1.5) Antibody from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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CD4 (GK1.5) Antibody from Santa Cruz Biotechnology, Inc.

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