The Fas Ligand Polyclonal Antibody, PE-Cy5 Conjugated from Bioss Inc. is a Rabbit Polyclonal antibody to fas ligand, and Faslg. This antibody recognizes Homo Sapiens, Human, Mouse, and Rat antigen. The Fas Ligand Polyclonal Antibody, PE-Cy5 Conjugated has been shown to work in the following applications: Flow Cytometry, and Western Blot.
Description
Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. May be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Binding to the decoy receptor TNFRSF6B/DcR3 modulates its effects. The FasL intracellular domain (FasL ICD) cytoplasmic form induces gene transcription inhibition