The CD95 Polyclonal Antibody, PE-Cy5 Conjugated from Bioss Inc. is a Rabbit Polyclonal antibody to Fas. This antibody recognizes Homo Sapiens, Human, Mouse, and Rat antigen. The CD95 Polyclonal Antibody, PE-Cy5 Conjugated has been shown to work in the following applications: Flow Cytometry, and Western Blot.
Description
Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both (By similarity)