The Jagged1 Polyclonal Antibody, Cy7 Conjugated from Bioss Inc. is a Rabbit Polyclonal antibody to JAG1, and jagged canonical Notch ligand 1. This antibody recognizes Homo Sapiens, Human, Mouse, and Rat antigen. The Jagged1 Polyclonal Antibody, Cy7 Conjugated has been shown to work in the following applications: Immunofluorescence, and Western Blot.
Description
The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis. [provided by RefSeq]