PERK(Thr980) Polyclonal Antibody, PE-Cy7 Conjugated bs-3330R-PE-Cy7 from Bioss Inc.

Description

Phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation and thus to a rapid reduction of translational initiation and repression of global protein synthesis. Serves as a critical effector of unfolded protein response (UPR)-induced G1 growth arrest due to the loss of cyclin-D1 (CCND1). Involved in control of mitochondrial morphology and function

Product Specs
ItemPERK(Thr980) Polyclonal Antibody, PE-Cy7 Conjugated
CompanyBioss Inc.
Price $488.00Supplier Page View Company Product Page
Catalog Numberbs-3330R-PE-Cy7
Quantity100ul, 20ul
ApplicationsWB, FCM
Concentration1ug/uL
Conjugate/TagPE-Cy7
Absorbance / Excitation488nm
FormatAqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol
ReactivityHuman, Mouse, Rat
TargetPERK Thr980
IsotypeIgG
Molecular Weight119kDa
HostRabbit
Antibody TypeConjugated Primary Antibody
ImmunogenKLH conjugated synthesised phosphopeptide derived from human PERK around the phosphorylation site of Thr981
Emission785nm
NCBI Gene AliasesPerk, Pek
ClonalityPolyclonal
NCBI Full Gene Nameeukaryotic translation initiation factor 2 alpha kinase 3
ModificationsThr980