Bioss Inc.'s Cathepsin K Polyclonal Antibody, FITC Conjugated is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Immunofluorescence, and Western Blot. The Cathepsin K Polyclonal Antibody, FITC Conjugated was generated using Cathepsin K, and CTSK as the antigen and it reacts with Mouse, and Rat.
Description
The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. This gene may be subject to RNA editing. [provided by RefSeq, Jul 2008]