The DNA PK/PRKDC(Thr2609) Antibody, Cy3 Conjugated from Bioss Inc. is a Rabbit Polyclonal antibody to PRKDC, and protein kinase, DNA-activated, catalytic subunit. This antibody recognizes Homo Sapiens, Human, and Mouse antigen. The DNA PK/PRKDC(Thr2609) Antibody, Cy3 Conjugated has been shown to work in the following applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry - fixed, and Immunohistochemistry - frozen.
Description
DNA PK is the key component of the non-homologous end-joining (NHEJ) pathway of DSB repair in mammalian cells. DNA PK consists of a heterodimeric DNA-binding subunit (Ku70/80) and an approximately 465 kDa catalytic subunit (DNA PKcs). DNA PKcs is a serine/threonine protein kinase whose activity is greatly stimulated by its recruitment to DNA breaks by the Ku heterodimer