Chk2 (B-4) Antibody sc-17748 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemChk2 (B-4) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-17748
Antibody TypePrimary Antibodies
NCBI Gene AliasesPP1425, CDS1, CHK2, hCds1, RAD53, HuCds1, LFS2
ApplicationsWB, IP, IF, IHC(P), ELISA
Quantity200 µg/ml
Reactivityhuman
CloneB-4
FormatPurified
ClonalityMonoclonal
Hostmouse
Conjugate/TagUnconjugated
NCBI Full Gene Namecheckpoint kinase 2
TargetChk2
IsotypeIgG1

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) In Vitro and In Vivo Comparative Analysis of Muscle Regenerative Processes Induced by Different Microcurrent Waveforms in Skeletal Muscle AtrophyInternational Journal of Molecular SciencesSeptember 24, 2025Yoon-Jin Lee, Eun Sang Kwon, Yong Suk Moon, Dong Rak KwonCHK1(1:500) (sc-8408, Santa Cruz Biotechnology), p-CHK2 (1:500) (#2197, cell signaling), CHK2(1:500) (sc-17748, Santa Cruz Biotechnology), PECAM-1 (sc-376764, Santa Cruz Biotechnology), PCNA(sc-56, Santa Cruz Biotechnology),

(2) The Neuroprotective Effects of Peripheral Nerve Microcurrent Stimulation Therapy in a Rat Model of Middle Cerebral Artery OcclusionInternational Journal of Molecular SciencesSeptember 18, 2024Yoon-Jin Lee, Eun Sang Kwon, Yong Suk Moon, Jeong-Rang Jo, Dong Rak KwonChk1 (1:500, sc-8408; Santa Cruz Biotechnology), p-Chk2 (1:250, #2197; Cell Signalling), Chk2 (1:500, sc-17748; Santa Cruz Biotechnology), and β-actin (1:1000, A2228; Sigma-Aldrich Corp.), all diluted in 5% casein

(3) (+)-Cyanidan-3-ol inhibits epidermoid squamous cell carcinoma growth via inhibiting AKT/mTOR signaling through modulating CIP2A-PP2A axisPhytomedicine : international journal of phytotherapy and phytopharmacologyJuly 1, 2022Monga J, Suthar SK, Rohila D, Joseph A, Chauhan CS, Sharma M.

(4) A pipecolic acid-rich branched cyclic depsipeptide ulleungamide C from a Streptomyces species induces G0/G1 cell cycle arrest in promyelocytic leukemia cellsThe Journal of antibioticsMarch 1, 2021Son S, Jang M, Lee B, Jang JP, Hong YS, Kim BY, Ko SK, Jang JH, Ahn JS.

(5) Targeting RECQL5 Functions, by a Small Molecule, Selectively Kills Breast Cancer in Vitro and in VivoJournal of medicinal chemistryFebruary 11, 2021Chakraborty S, Dutta K, Gupta P, Das A, Das A, Ghosh SK, Patro BS.

(6) A Disease-Causing Single Amino Acid Deletion in the Coiled-Coil Domain of RAD50 Impairs MRE11 Complex Functions in Yeast and HumansCell reportsDecember 29, 2020Chansel-Da Cruz M, Hohl M, Ceppi I, Kermasson L, Maggiorella L, Modesti M, de Villartay JP, Ileri T, Cejka P, Petrini JHJ, et al.anti-RAD50 (Genetex 13B3, GTX 70228; 1:500), anti-NBS1 (Novus, NB100-143E1; 1:500), anti-CHK2 (Santa Cruz, SC17748; 1:1,000). Immunofluorescence For P-KAP1, RPA32 and RAD51 detection, cells were cultured on coverslips

(7) Identification of lineariifolianoid A as a novel dual NFAT1 and MDM2 inhibitor for human cancer therapyJournal of biomedical researchJuly 1, 2016Qin JJ, Sarkar S, Voruganti S, Agarwal R, Wang W, Zhang R.

(8) Inulanolide A as a new dual inhibitor of NFAT1-MDM2 pathway for breast cancer therapyOncotargetMay 31, 2016Qin JJ, Wang W, Sarkar S, Voruganti S, Agarwal R, Zhang R.

(9) Single-stranded DNA oligomers stimulate error-prone alternative repair of DNA double-strand breaks through hijacking Ku proteinNucleic acids researchDecember 2, 2015Yuan Y, Britton S, Delteil C, Coates J, Jackson SP, Barboule N, Frit P, Calsou P.

(10) Dual phosphoinositide 3-kinase/mammalian target of rapamycin inhibitor is an effective radiosensitizer for colorectal cancerCancer lettersFebruary 28, 2015Chen YH, Wei MF, Wang CW, Lee HW, Pan SL, Gao M, Kuo SH, Cheng AL, Teng CM.

(11) Low CHD5 expression activates the DNA damage response and predicts poor outcome in patients undergoing adjuvant therapy for resected pancreatic cancerOncogeneNovember 20, 2014Hall WA, Petrova AV, Colbert LE, Hardy CW, Fisher SB, Saka B, Shelton JW, Warren MD, Pantazides BG, Gandhi K, et al.(Millipore, 05-636), H2AX (Bethyl, Montgomery, TX, USA, A300-082A), CHK2 (Santa Cruz, Dallas, TX, USA, sc-17748) and GAPDH (GeneTex, Irvine, CA, USA, GTX627408) followed by LI-COR IRDye secondary antibodies. Detection and

(12) A role for DNA polymerase θ in the timing of DNA replicationNature communicationsJuly 3, 2014Fernandez-Vidal A, Guitton-Sert L, Cadoret JC, Drac M, Schwob E, Baldacci G, Cazaux C, Hoffmann JS.(NA18, 1:1,000, Calbiochem), 8 Phospho-RPA32 (S4/S8) (A300-245A, 1:1,000, Bethyl Laboratories), Chk2 (sc17748, 1:1,000, Santa Cruz Biotechnology), Phospho-Chk2 (Thr68) (2197, 1:1,000, Cell Signaling), horseradish

(13) Doxorubicin promotes transcriptional upregulation of Cdc25B in cancer cells by releasing Sp1 from the promoterOncogeneOctober 17, 2013Dalvai M, Mondesert O, Bugler B, Manenti S, Ducommun B, Dozier C.

(14) Cell cycle-dependent localization of CHK2 at centrosomes during mitosisCell divisionMay 16, 2013Chouinard G, Clément I, Lafontaine J, Rodier F, Schmitt E.

(15) FoxM1 inhibition sensitizes resistant glioblastoma cells to temozolomide by downregulating the expression of DNA-repair gene Rad51Clinical cancer research : an official journal of the American Association for Cancer ResearchNovember 1, 2012Zhang N, Wu X, Yang L, Xiao F, Zhang H, Zhou A, Huang Z, Huang S.

(16) RAC1 GTPase plays an important role in γ-irradiation induced G2/M checkpoint activationBreast cancer research : BCRApril 11, 2012Yan Y, Greer PM, Cao PT, Kolb RH, Cowan KH.

(17) ERK1/2 signaling plays an important role in topoisomerase II poison-induced G2/M checkpoint activationPloS oneJanuary 1, 2012Kolb RH, Greer PM, Cao PT, Cowan KH, Yan Y.

(18) Protein phosphatase 2A has an essential role in the activation of gamma-irradiation-induced G2/M checkpoint responseOncogeneJuly 29, 2010Yan Y, Cao PT, Greer PM, Nagengast ES, Kolb RH, Mumby MC, Cowan KH.

(19) Mitotic DNA damage response: Polo-like kinase-1 is dephosphorylated through ATM-Chk1 pathwayCell cycle (Georgetown, Tex.)June 15, 2010Lee HJ, Hwang HI, Jang YJ.

(20) Cellular effects of genotoxic stress and gene silencing of the checkpoint kinases in human oral cellsJournal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral PathologyAugust 1, 2009Ji JH, Jang YJ.

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Chk2 (B-4) Antibody

Chk2 (B-4) Antibody from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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Chk2 (B-4) Antibody from Santa Cruz Biotechnology, Inc.

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