The E2F1 (Ser364) Polyclonal Antibody, PE-Cy7 Conjugated from Bioss Inc. is a Rabbit Polyclonal antibody to E2F Transcription Factor 1, and E2F1. This antibody recognizes Homo Sapiens, Human, and Rat antigen. The E2F1 (Ser364) Polyclonal Antibody, PE-Cy7 Conjugated has been shown to work in the following applications: Flow Cytometry, and Western Blot.
Description
Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F1 binds preferentially RB1 in a cell-cycle dependent manner. It can mediate both cell proliferation and TP53/p53-dependent apoptosis