The Histone H2A.x Polyclonal Antibody, Cy5 Conjugated from Bioss Inc. is a Rabbit Polyclonal antibody to H2A.X variant histone, and H2AX. This antibody recognizes Homo Sapiens, Human, Mouse, Rat, Bovine, Canine, and Porcine antigen. The Histone H2A.x Polyclonal Antibody, Cy5 Conjugated has been shown to work in the following applications: Immunofluorescence, and Western Blot.
Description
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. [provided by RefSeq, Jul 2008]