Bioss Inc.'s Smoothened homolog Polyclonal Antibody, PE-Cy5 Conjugated is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Western Blot. The Smoothened homolog Polyclonal Antibody, PE-Cy5 Conjugated was generated using SMO as the antigen and it reacts with Homo Sapiens, Human, and Mouse.
Description
G protein-coupled receptor that probably associates with the patched protein (PTCH) to transduce the hedgehog's proteins signal. Binding of sonic hedgehog (SHH) to its receptor patched is thought to prevent normal inhibition by patched of smoothened (SMO). Required for the accumulation of KIF7 and GLI3 in the cilia