Bioss Inc.'s GLUR3 Polyclonal Antibody, PE-Cy7 Conjugated is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Flow Cytometry. The GLUR3 Polyclonal Antibody, PE-Cy7 Conjugated was generated using GRIA3 as the antigen and it reacts with Homo Sapiens, and Human.
Description
Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate