B7-2 (BU63) Antibody sc-19617 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemB7-2 (BU63) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-19617
Antibody TypePrimary Antibodies
NCBI Gene AliasesB70, B7.2, ETC-1, LAB72, B7-2, Ly-58, CLS1, CD28LG2, B7, MB7-2, Ly58, MB7, TS/A-2, Cd28l2
CloneBU63
Quantity200 µg/ml
Reactivitymouse, rat, human
ApplicationsWB, IP, IF, FCM
FormatPurified
ClonalityMonoclonal
Hostmouse
Conjugate/TagUnconjugated
NCBI Full Gene NameCD86 molecule, CD86 antigen
TargetB7-2
IsotypeIgG1

Questions and Answers

Can this antibody be used to study the role of CD86 in B-cell infections by hepatitis C virus?

Yes, the B7-2 (BU63) antibody has been shown to work in studies examining CD86 as a co-receptor for lymphotropic hepatitis C virus infection in B cells. This research indicates that CD86 plays a significant role in the inhibition of memory B-cell function during HCV infection, as detailed in the study by Chen et al. ().

Is this antibody effective for immunoblotting applications?

The B7-2 (BU63) antibody has been utilized successfully in immunoblotting, as evidenced by its use in various studies, including those that analyze protein expression in different cell types and conditions (, , ).

What species can this antibody react with, and is it suitable for flow cytometry?

The B7-2 (BU63) antibody is reactive with mouse, human, and rat species. It has also been shown to be effective for flow cytometry applications, allowing for the analysis of CD86 expression on various immune cells (, ).

Are there any specific applications where this antibody has been cited in the literature?

Yes, the B7-2 (BU63) antibody has been cited in multiple applications, including Western blotting, flow cytometry, immunofluorescence, and immunoprecipitation, as demonstrated in various studies that explore immune responses and cell signaling pathways (, ).

Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Bacillus Calmette-Guérin immunotherapy-induced extracellular vesicles promote antitumor immunity in bladder cancerFront ImmunolApril 13, 2026Carlos J. Ortiz-Bonilla, Ryan D. Molony, Hiroshi Miyamoto, Edward Messing, Yi-Fen Leeantibodies: B7-1 (1:300, H-208, sc-9091, rabbit polyclonal IgG, Santa Cruz Biotechnology), B7-2 (1:300, BU63, sc-19617, mouse monoclonal IgG1, Santa Cruz Biotechnology), MHC Class I (1:700, H-300, sc25619, rabbit polyclonal

(2) Bioinspired lipid droplets nanoplatform for periodontitis therapy: Integrated antibacterial, mitochondrial repair, and immunomodulatory functionsMaterials Today BioApril 1, 2026Xin Wang, Chenfang Ban, Xuejing Li, Jin Wang, Bangping Cao, Wenjing Wu, Zhanwei Zhang, Jiansheng Suprimary antibodies against F4/80 (1:50, Abmart, China, #MU124812) and CD86 (1:100, Santa Cruz, USA, #sc-19617) or CD206 (1:1000, Abcam, USA, #ab64693), FITC-conjugated Goat Anti-Rat IgG (1:100, Proteintech, USA,

(3) Ferroptosis-dependent small extracellular vesicles ULK1 enhances mitophagy and suppresses breast cancer migrationHereditasJanuary 26, 2026Anan Wang, Min Chen, Yonghui Luo, Li Li, Jiahao Rong, Lei Liu, Chenghao Yi14600-1-AP 1:4000 dilution), anti-TOM20 (Proteintech, 11802-1-AP, 1:20000 dilution), anti-CD86 (Santa cruz, sc-19617, 1:200 dilution), anti-206 (Proteintech, 18704-1-AP, 1:2000 dilution), and anti-GAPDH (Proteintech,

(4) Poly-D,L-Lactic Acid Filler Increases Hair Growth by Modulating Hair Follicular Stem Cells in Aged SkinCellsDecember 19, 2025Seyeon Oh, Jino Kim, Hosung Choi, Hwa Jung Yoo, Kuk Hui Son, Kyunghee Byunincubated for 30 min at 4 °C in the dark with anti-CD86 (1 μg/1 × 105 cells; Santa Cruz Biotechnology, #sc-19617, Westminster, CO, USA), anti-CD206 (1 μg/1 × 105 cells; Novus Biogicals LLC, #NBP1-90020, Dallas, TX,

(5) CX3CL1 deficiency ameliorates acute kidney injury by inhibiting macrophage mitochondrial dysfunction and mtDNA-cGAS-STING signalingCell Death DiscoveryDecember 13, 2025Qiming Gong, Fahui Liu, Yuqing Huang, Dehui Li, Tingting Zhou, Chen Zeng, Yan Jiang, Huang Wei, Yong Xu(ab178945), and MTCO1 (ab14705) were obtained from Abcam (Cambridge, USA). Antibodies against CD86 (sc-19617), IL-10 (sc-8438), TNFα (sc-52746), Tomm20 (sc-17764), dsDNA (sc-58749), TFAM (sc-166965), and Bax (sc-20067)

(6) Fat-targeted small molecule alleviates abnormal adipose tissue remodeling in obesity via SIRT3-driven mitophagy and inflammasome inhibitionChin MedDecember 10, 2025Kegang Linghu, Longkun Hu, Yu-E. Wang, Yuxia Zhou, Yuanyuan Wang, Mingjun Shi, Lirong Liu, Hua Yu, Lei Tang, Ligen Lin, et al.CA, USA)",WB,1:500 SIRT5,SC-271635,"Santa Cruz Biotechnology (Santa Cruz, CA, USA)",WB,1:500 CD86,SC-19617,"Santa Cruz Biotechnology (Santa Cruz, CA, USA)",IHC,1:100 Perilipin-1,9349S,"Cell Signaling Technology

(7) Reprogramming mitochondrial metabolism and epigenetics of macrophages via miR-10a liposomes for atherosclerosis therapyNat CommunOctober 14, 2025Fei Fang, Erxiang Wang, Hanqiao Yang, Ting Zhao, Qiwei Wang, Zhen Zhang, Yang Song, Xiaoheng Liugoat serum. The sections were stained with the antibodies, including H3K9Ac (#9649, CST, USA), CD86 (#sc-19617, Santa Cruz, USA), iNOS (#33424, SAB, USA), and TFAM (mitochondrial transcription factor A, #29688,

(8) N-Lactoyl-Phenylalanine modulates lipid metabolism in microglia/macrophage via the AMPK-PGC1α-PPARγ pathway to promote recovery in mice with spinal cord injuryJ NeuroinflammationJune 27, 2025Weiyang Ying, Weidong Weng, Peifang Wang, Chi Pan, Jiani Qiu, Qianqian Huang, Gonghao Zhan, Xiaoli Chen(Wuhan, China). Antibodies CD36 (DF13262) was provided by Affinity (Suzhou, China). Antibodies CD86 (sc-19617) was provided by Santa Cruz (California, USA). Antibodies IL1β (516288), IL10 (502171) and β actin (380624)

(9) High glucose promotes macrophage switching to the M1 phenotype via the downregulation of STAT-3 mediated autophagyPLOS ONEDecember 31, 2024Yu Zhao, Yuteng Jiang, Fengmei Wang, Li Sun, Mengyuan Ding, Liyuan Zhang, Beibei Wu, Xiaoliang Zhangtechnique. Sections were incubated with primary mouse anti-CD68 (Santa Cruz, SC-59103), CD86 (Santa Cruz, SC-19617) followed by incubation with an appropriate secondary antibody. The immunostaining was visualized using

(10) Vaso-Lock for sutureless anastomosis in a pig arteriovenous loop modelBiomaterialsJuly 1, 2024Li X, Young ER, Martin C, Ribaudo JG, Zaghloul M, Roberts S, Meade R, Arif B, Moritz WR, Madira S, et al.pan-macrophages (CD68; LS-C392470, Absolute Biotech, Seattle, Washington), pro-inflammatory macrophages (CD86; sc-19617, Santa Cruz Biotechnology, Inc., Dallas, Texas), and immunoregulatory macrophages (CD206; sc-376,108,

(11) High glucose impairs cognitive function through inducing mitochondrial calcium overload in Treg cellsiScienceJanuary 19, 2024Hui Y, Kuang L, Zhong Y, Tang Y, Xu Z, Zheng T.AB_2144945" Anti-CD206,Proteintech,"Cat# 18704-1-AP, RRID: AB_10597232" Anti-CD86,Santa Cruz Biotechnology,"Cat# sc-19617, RRID: AB_627201" Anti-CD86,Proteintech,"Cat# 13395-1-AP, RRID: AB_2074882" Goat anti-mouse IgG,Proteintech,Cat#

(12) Assessing the response of human primary macrophages to defined fibrous architectures fabricated by melt electrowritingBioactive materialsMarch 1, 2023Mondadori C, Chandrakar A, Lopa S, Wieringa P, Talò G, Perego S, Lombardi G, Colombini A, Moretti M, Moroni L.

(13) Nonenzymatic function of DPP4 promotes diabetes-associated cognitive dysfunction through IGF-2R/PKA/SP1/ERp29/IP3R2 pathway-mediated impairment of Treg function and M1 microglia polarizationMetabolism: clinical and experimentalJanuary 1, 2023Hui Y, Xu Z, Li J, Kuang L, Zhong Y, Tang Y, Wei J, Zhou H, Zheng T.

(14) Pharmacological Inhibition of Lysine-Specific Demethylase 1A Reduces Atherosclerotic Lesion Formation in Apolipoprotein E-Deficient Mice by a Mechanism Involving Decreased Oxidative Stress and Inflammation; Potential Implications in Human AtherosclerosisAntioxidants (Basel, Switzerland)December 1, 2022Manea SA, Vlad ML, Lazar AG, Muresian H, Simionescu M, Manea A.

(15) Cyanidin-3-O-Glucoside Regulates the M1/M2 Polarization of Microglia via PPARγ and Aβ42 Phagocytosis Through TREM2 in an Alzheimer's Disease ModelMolecular neurobiologyAugust 1, 2022Sanjay, Shin JH, Park M, Lee HJ.No. CFN99740) was purchased from ChemFaces (Wuhan, Hubei, China). Specific antibodies against CD86 (sc-19617), CD206 (sc-58986), CD163 (sc-20066), and TREM2 (sc-373828) were purchased from Santa Cruz Biotechnology

(16) Bladder Cancer Extracellular Vesicles Elicit a CD8 T Cell-Mediated Antitumor ImmunityInternational journal of molecular sciencesMarch 8, 2022Ortiz-Bonilla CJ, Uccello TP, Gerber SA, Lord EM, Messing EM, Lee YF.H-208, sc-9091, rabbit polyclonal IgG, Santa Cruz Biotechnology, Dallas, TX, USA), B7-2 (1:300, BU63, sc-19617, mouse monoclonal IgG1, Santa Cruz Biotechnology), MHC Class I (1:700, H-300, sc25619, rabbit polyclonal

(17) Distinct roles in phagocytosis of the early and late increases of cell surface calreticulin induced by oxaliplatinBiochemistry and biophysics reportsMarch 1, 2022Matsusaka K, Azuma Y, Kaga Y, Uchida S, Takebayashi Y, Tsuyama T, Tada S.

(18) CHI3L1 enhances melanoma lung metastasis via regulation of T cell co-stimulators and CTLA-4/B7 axisFrontiers in immunologyJanuary 1, 2022Ma B, Kamle S, Akosman B, Khan H, Lee CM, Lee CG, Elias JA.

(19) Rab7b regulates dendritic cell migration by linking lysosomes to the actomyosin cytoskeletonJournal of cell scienceSeptember 15, 2021Vestre K, Persiconi I, Borg Distefano M, Mensali N, Guadagno NA, Bretou M, Wälchli S, Arnold-Schrauf C, Bakke O, Dalod M, et al.R&D Systems; 10 µl/test), CD11c (BD559877, BD Biosciences; 20 µl/test), CD83 (sc19678; 20 µl/test) and CD86 (sc19617; 20 µl/test) (both from Santa Cruz Technology). To check the expression of the TCR Radium-1 a Vβ3-FITC

(20) Interleukin-17 induced by cumulative mild stress promoted depression-like behaviors in young adult miceMolecular brainJanuary 13, 2021Kim J, Suh YH, Chang KA.,For Western blot analysis,For Western blot analysis,For Western blot analysis Anti-CD86,Mouse,1:200,Santa cruz (sc-19617) Anti-GAPDH,Rabbit,1:5000,Bioworld (A531) Anti-IL-1β,Rabbit,1:2000,Abcam (ab9722) Anti-IL-6,Rabbit,1:500,MyBioSource

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B7-2 (BU63) Antibody

B7-2 (BU63) Antibody from Santa Cruz Biotechnology, Inc.

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Questions and Answers

Santa Cruz Biotechnology, Inc.

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B7-2 (BU63) Antibody from Santa Cruz Biotechnology, Inc.

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