The FOXL2 Polyclonal Antibody, Cy5 Conjugated from Bioss Inc. is a Rabbit Polyclonal antibody to forkhead box L2, and FOXL2. This antibody recognizes Homo Sapiens, Human, Mouse, Rat, and Bovine antigen. The FOXL2 Polyclonal Antibody, Cy5 Conjugated has been shown to work in the following applications: Immunofluorescence, and Western Blot.
Description
Transcriptional regulator. Critical factor essential for ovary differentiation and maintenance, and repression of the genetic program for somatic testis determination. Prevents trans-differentiation of ovary to testis throught transcriptional repression of the Sertoli cell-promoting gene SOX9 (By similarity). Has apoptotic activity in ovarian cells. Suppresses ESR1-mediated transcription of PTGS2/COX2 stimulated by tamoxifen (By similarity). Is a regulator of CYP19 expression (By similarity). Participates in SMAD3-dependent transcription of FST via the intronic SMAD-binding element (By similarity). Is a transcriptional repressor of STAR. Activates SIRT1 transcription under cellular stress conditions. Activates transcription of OSR2