The Bcl-2 Polyclonal Antibody, PE Conjugated from Bioss Inc. is a Rabbit Polyclonal antibody to BCL2, and BCL2 apoptosis regulator. This antibody recognizes Homo Sapiens, Human, Mouse, and Rat antigen. The Bcl-2 Polyclonal Antibody, PE Conjugated has been shown to work in the following applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry - fixed, Immunohistochemistry - frozen, and Western Blot.
Description
Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1)