The TRAILR2/DR5 Antibody, PE-Cy7 Conjugated from Bioss Inc. is a Rabbit Polyclonal antibody to TNFRSF10B. This antibody recognizes Homo Sapiens, and Human antigen. The TRAILR2/DR5 Antibody, PE-Cy7 Conjugated has been shown to work in the following applications: Western Blot.
Description
Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. Essential for ER stress-induced apoptosis (By similarity)