Bioss Inc.'s PTPN11 (Tyr584) Polyclonal Antibody, Cy7 Conjugated is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry - fixed, Immunohistochemistry - frozen, and Western Blot. The PTPN11 (Tyr584) Polyclonal Antibody, Cy7 Conjugated was generated using protein tyrosine phosphatase non-receptor type 11, and PTPN11 as the antigen and it reacts with Homo Sapiens, Human, Mouse, and Rat.
Description
Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Dephosphorylates ROCK2 at Tyr-722 resulting in stimulatation of its RhoA binding activity