The APH1a Polyclonal Antibody, Biotin Conjugated from Bioss Inc. is a Rabbit Polyclonal antibody to aph1a. This antibody recognizes Homo Sapiens, Human, and Rat antigen. The APH1a Polyclonal Antibody, Biotin Conjugated has been shown to work in the following applications: EIA, Immunoassay, ELISA, Immunohistochemistry, Immunohistochemistry - fixed, Immunohistochemistry - frozen, and Western Blot.
Description
Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents a stabilizing cofactor for the presenilin homodimer that promotes the formation of a stable complex