Bioss Inc.'s DNA PK/PRKDC(Thr2609) Antibody, RBITC Conjugated is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry - fixed, and Immunohistochemistry - frozen. The DNA PK/PRKDC(Thr2609) Antibody, RBITC Conjugated was generated using PRKDC, and protein kinase, DNA-activated, catalytic subunit as the antigen and it reacts with Homo Sapiens, Human, and Mouse.
Description
DNA PK is the key component of the non-homologous end-joining (NHEJ) pathway of DSB repair in mammalian cells. DNA PK consists of a heterodimeric DNA-binding subunit (Ku70/80) and an approximately 465 kDa catalytic subunit (DNA PKcs). DNA PKcs is a serine/threonine protein kinase whose activity is greatly stimulated by its recruitment to DNA breaks by the Ku heterodimer