The TTF1 Polyclonal Antibody, Cy5 Conjugated from Bioss Inc. is a Rabbit Polyclonal antibody to NKX2-1. This antibody recognizes Human, Mouse, and Rat antigen. The TTF1 Polyclonal Antibody, Cy5 Conjugated has been validated for the following applications: Flow Cytometry, Immunocytochemistry, and Immunofluorescence.
Description
Transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. Crucial in the maintenance of the thyroid differentiation phenotype. May play a role in lung development and surfactant homeostasis. Activates the transcription of GNRHR and plays a role in enhancing the circadian oscillation of its gene expression. Represses the transcription of the circadian transcriptional repressor NR1D1 (By similarity)