Bioss Inc.'s ATG4A Polyclonal Antibody, HRP Conjugated is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: EIA, Immunoassay, ELISA, Immunohistochemistry, Immunohistochemistry - fixed, and Immunohistochemistry - frozen. The ATG4A Polyclonal Antibody, HRP Conjugated was generated using ATG4A as the antigen and it reacts with Homo Sapiens, Human, Mouse, and Rat.
Description
ATG4A is a cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes