Bioss Inc.'s Jagged1 Polyclonal Antibody, Cy5.5 Conjugated is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Immunofluorescence, and Western Blot. The Jagged1 Polyclonal Antibody, Cy5.5 Conjugated was generated using JAG1, and jagged canonical Notch ligand 1 as the antigen and it reacts with Homo Sapiens, Human, Mouse, and Rat.
Description
The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis. [provided by RefSeq]