The Jagged1 Polyclonal Antibody, PE-Cy5 Conjugated from Bioss Inc. is a Rabbit Polyclonal antibody to JAG1, and jagged canonical Notch ligand 1. This antibody recognizes Homo Sapiens, Human, Mouse, and Rat antigen. The Jagged1 Polyclonal Antibody, PE-Cy5 Conjugated has been shown to work in the following applications: Western Blot.
Description
The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis. [provided by RefSeq]