The APAF1 Polyclonal Antibody, PE Conjugated from Bioss Inc. is a Rabbit Polyclonal antibody to APAF1. This antibody recognizes Homo Sapiens, Human, Mouse, and Rat antigen. The APAF1 Polyclonal Antibody, PE Conjugated has been shown to work in the following applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry - fixed, and Immunohistochemistry - frozen.
Description
Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis