The PITX3 Polyclonal Antibody, PE-Cy5 Conjugated from Bioss Inc. is a Rabbit Polyclonal antibody to PITX3. This antibody recognizes Homo Sapiens, Human, Mouse, Rat, and Bovine antigen. The PITX3 Polyclonal Antibody, PE-Cy5 Conjugated has been shown to work in the following applications: Western Blot.
Description
The transcription factor PITX3 is expressed selectively in the midbrain and regulates the differentiation and survival of dopaminergic neurons. Lack of this factor results in a degeneration similar to that seen in Parkinson's disease. PITX3 is also important in eye developement; mutations of the PITX3 gene have been associated with a familial form of cataracts