Bioss Inc.'s Cryopyrin Polyclonal Antibody, Cy7 Conjugated is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Immunofluorescence, and Western Blot. The Cryopyrin Polyclonal Antibody, Cy7 Conjugated was generated using NLRP3 as the antigen and it reacts with Homo Sapiens, Human, Mouse, Rat, and Canine.
Description
May function as an inducer of apoptosis. Interacts selectively with ASC and this complex may function as an upstream activator of NF-kappa-B signaling. Inhibits TNF-alpha induced activation and nuclear translocation of RELA/NF-KB p65. Also inhibits transcriptional activity of RELA. Activates caspase-1 in response to a number of triggers including bacterial or viral infection which leads to processing and release of IL1B and IL18