Bioss Inc.'s GEF H1 (Ser886) Polyclonal Antibody, PE-Cy5 Conjugated is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Western Blot. The GEF H1 (Ser886) Polyclonal Antibody, PE-Cy5 Conjugated was generated using ARHGEF2 as the antigen and it reacts with Homo Sapiens, Human, and Mouse.
Description
GEF-H1 is a Rho guanine nucleotide exchange factor that localizes to microtubules and regulates Rho activity in response to microtubule destabilization (loss of interaction between GEF-H1 and microtubules leads to activation of Rho). This protein has also been shown to localize to tight junctions and modulate polarized cell permeability