ASC Antibody AF3805 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemASC Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $489.00Supplier Page View Company Product Page
Catalog NumberAF3805
ApplicationsWestern Blot,Immunohistochemistry-Paraffin,Simple Western,Immunocytochemistry
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
Conjugate/TagUnconjugated
ReactivityHuman,Mouse,Rat
Quantity100 ug (also 25 ug)
IsotypeIgG
HostGoat
NCBI Full Gene NamePYD and CARD domain containing
ImmunogenE. coli-derived recombinant human ASC, Leu112-Ser195, Accession # Q9ULZ3
ConcentrationLYOPH
PurityAntigen Affinity-purified
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution
ValidationKnockout Validated
ClonalityPolyclonal
TargetASC
NCBI Gene AliasesASC, TMS, TMS1, CARD5, TMS-1

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Specificity: Detects human ASC in Western blots.

Sizes Available: 100 ug (also 25 ug)

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Downregulation of miR-137 Facilitates CD4+ T Cell Pyroptosis in Systemic Lupus Erythematosus via Stimulating AMPK PathwayJournal of immunology researchJanuary 1, 2023Gong A, Mi L, Wei F, Zhuang Y, Song Y, Pan C, Zhang X, Lin G, Wu Z, Liu Y.

(2) M24B aminopeptidase inhibitors selectively activate the CARD8 inflammasomeNature chemical biologyMay 1, 2022Rao SD, Chen Q, Wang Q, Orth-He EL, Saoi M, Griswold AR, Bhattacharjee A, Ball DP, Huang HC, Chui AJ, et al.

(3) Bone mesenchymal stem cells-derived miR-223-3p-containing exosomes ameliorate lipopolysaccharide-induced acute uterine injury via interacting with endothelial progenitor cellsBioengineeredDecember 1, 2021Liu Y, Zhang S, Xue Z, Zhou X, Tong L, Liao J, Pan H, Zhou S.the primary antibodies against NLRP3 (1:1500, Catalog MAB7578, R&D system, USA), ASC (1:1000, Catalog AF3805, R&D system, USA), N-Gasdermin D (1:1000, Catalog ab209845, Abcam, UK), GAPDH (1:2000, Catalog 2275-PC-100,

(4) Promoter Methylation Leads to Decreased ZFP36 Expression and Deregulated NLRP3 Inflammasome Activation in Psoriatic FibroblastsFrontiers in medicineJanuary 1, 2020Bertesi M, Fantini S, Alecci C, Lotti R, Martello A, Parenti S, Carretta C, Marconi A, Grande A, Pincelli C, et al.Cell Signaling Technologies, Danvers, MA, USA), TTP (#71632S Cell Signaling Technologies, Danvers, MA, USA), ASC (AF3805, R&D systems, Minneapolis, MN, USA), and tubulin (MAB1864, clone YL1/2, Millipore Corporation, Burlington,

(5) Magnesium Sulfate Mitigates the Progression of Monocrotaline Pulmonary Hypertension in RatsInternational journal of molecular sciencesSeptember 18, 2019Chang CY, Shih HJ, Huang IT, Tsai PS, Chen KY, Huang CJ.

(6) Caspase-1 interdomain linker cleavage is required for pyroptosisLife science allianceJanuary 1, 0001"Ball DP, Taabazuing CY, Griswold AR, Orth EL, Rao SD, Kotliar IB, Vostal LE, Johnson DC, Bachovchin DA."Abcam), CARD8 C terminus rabbit polyclonal Ab (Ab24186; Abcam), human ASC sheep polyclonal antibody (AF3805; R&D systems), GAPDH rabbit monoclonal Ab (14C10; Cell Signaling Technology), NLuc (Lg-BiT) polyclonal

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ASC Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

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ASC Antibody from R&D Systems, a Bio-Techne Brand

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