CCR5/CD195 Polyclonal Antibody, PE Conjugated bs-2514R-PE from Bioss Inc.

Description

Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Acts as a coreceptor (CD4 being the primary receptor) for HIV-1 R5 isolates

Product Specs
ItemCCR5/CD195 Polyclonal Antibody, PE Conjugated
CompanyBioss Inc.
Price $478.00Supplier Page View Company Product Page
Catalog Numberbs-2514R-PE
Quantity100ul
ApplicationsWB, FCM, IF(IHC-P), IF(IHC-F), IF(ICC)
Concentration1ug/uL
Conjugate/TagPE
Absorbance / Excitation496,564nm
FormatAqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol
ReactivityHuman
TargetCCR5/CD195
IsotypeIgG
Molecular Weight40kDa
HostRabbit
Antibody TypeConjugated Primary Antibody
ImmunogenKLH conjugated synthetic peptide derived from human CCR-5 C-terminus
Emission578nm
NCBI Gene AliasesCCCKR5, CKR-5, CD195, CCR-5, CKR5, CC-CKR-5, IDDM22, CMKBR5
ClonalityPolyclonal
NCBI Full Gene NameC-C motif chemokine receptor 5

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Questions and Answers

What species does this antibody work with for my experiments?

The CCR5/CD195 Polyclonal Antibody is reactive with human, mouse, and rat samples, making it suitable for a variety of experimental models.

Can this antibody be used for flow cytometry applications?

Yes, this antibody has been shown to work in flow cytometry applications, allowing for the analysis of CCR5 expression on cell surfaces.

How does this antibody interact with the CCR5 receptor in terms of its biological function?

The CCR5 receptor is involved in the signaling of inflammatory CC-chemokines and acts as a coreceptor for HIV-1 R5 isolates, which may be relevant for studies on immune response and HIV research.

What is the immunogen used for this antibody, and why is it important?

The immunogen for this antibody is a KLH-conjugated synthetic peptide derived from the C-terminus of human CCR5. This specificity is crucial for generating an antibody that accurately recognizes the CCR5 protein in various applications.