The Histone H2A Polyclonal Antibody, PE-Cy5 Conjugated from Bioss Inc. is a Rabbit Polyclonal antibody to H2A clustered histone 20, and H2AC20. This antibody recognizes Homo Sapiens, Human, Mouse, and Rat antigen. The Histone H2A Polyclonal Antibody, PE-Cy5 Conjugated has been shown to work in the following applications: Flow Cytometry, and Western Blot.
Description
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling