The Cryopyrin Polyclonal Antibody, PE-Cy7 Conjugated from Bioss Inc. is a Rabbit Polyclonal antibody to NLRP3. This antibody recognizes Homo Sapiens, Human, Mouse, Rat, and Canine antigen. The Cryopyrin Polyclonal Antibody, PE-Cy7 Conjugated has been shown to work in the following applications: Western Blot.
Description
May function as an inducer of apoptosis. Interacts selectively with ASC and this complex may function as an upstream activator of NF-kappa-B signaling. Inhibits TNF-alpha induced activation and nuclear translocation of RELA/NF-KB p65. Also inhibits transcriptional activity of RELA. Activates caspase-1 in response to a number of triggers including bacterial or viral infection which leads to processing and release of IL1B and IL18