The BACE1 Polyclonal Antibody, PE-Cy7 Conjugated from Bioss Inc. is a Rabbit Polyclonal antibody to BACE1, and Beta-Secretase 1. This antibody recognizes Homo Sapiens, Human, Mouse, and Rat antigen. The BACE1 Polyclonal Antibody, PE-Cy7 Conjugated has been shown to work in the following applications: Flow Cytometry, and Western Blot.
Description
Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase