Bioss Inc.'s SNF5 Polyclonal Antibody, HRP Conjugated is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: EIA, Immunoassay, ELISA, Immunohistochemistry, Immunohistochemistry - fixed, and Immunohistochemistry - frozen. The SNF5 Polyclonal Antibody, HRP Conjugated was generated using SMARCB1 as the antigen and it reacts with Homo Sapiens, Human, and Mouse.
Description
SNF5 is involved in transcriptional activation. The SWI/SNF complex is required for the induced expression of a large number of genes. This complex alters chromatin structure to facilitate binding of gene-specific dedicated transcription factors. SNF5 also funtions as a tumor suppressor gene and is frequently mutated in malignant rhabdoid tumors. It is also involved in adipocyte differentiation