Bioss Inc.'s Runx3 Polyclonal Antibody, PE-Cy7 Conjugated is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Western Blot. The Runx3 Polyclonal Antibody, PE-Cy7 Conjugated was generated using RUNX family transcription factor 3, and RUNX3 as the antigen and it reacts with Homo Sapiens, Human, Mouse, Rat, Bovine, Canine, and Chicken/Bird.
Description
RUNX3 binds to the core site of murine Leukemia virus, the core sequences in the enhancer of the polyomavirus, and also to the enhancers of the T-cell receptor genes. May be involved in the control of cellular proliferation and/or differentiation (By similarity). Heterodimer of an alpha and a beta subunit. The alpha subunit binds DNA as a monomer and through the Runt domain.DNA-binding is increased by heterodimerization. Interacts with TLE1 and SUV39H1, Subcellular location in Nucleus