The AF10 Polyclonal Antibody, PE Conjugated from Bioss Inc. is a Rabbit Polyclonal antibody to MLLT10, and MLLT10 histone lysine methyltransferase DOT1L cofactor. This antibody recognizes Homo Sapiens, Human, and Rat antigen. The AF10 Polyclonal Antibody, PE Conjugated has been shown to work in the following applications: Flow Cytometry, and Western Blot.
Description
A chromosomal aberration involving MLLT10 is associated with acute leukemias. Translocation t(10;11)(p12;q23) with MLL/HRX. The result is a rogue activator protein.A chromosomal aberration involving MLLT10 is associated with diffuse histiocytic lymphomas. Translocation t(10;11)(p13;q14) with PICALM