The Bax Polyclonal Antibody, PE-Cy7 Conjugated from Bioss Inc. is a Rabbit Polyclonal antibody to BAX. This antibody recognizes Homo Sapiens, Human, Mouse, Rat, and Rabbit antigen. The Bax Polyclonal Antibody, PE-Cy7 Conjugated has been shown to work in the following applications: Flow Cytometry, and Western Blot.
Description
Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis