AAA Biotech, LLC's GM-CSF-R-alpha (CD116) Antibody is a Polyclonal antibody. This antibody has been shown to work in applications such as: Immunocytochemistry, and Western Blot. The GM-CSF-R-alpha (CD116) Antibody was generated using CSF2RA as the antigen and it reacts with Mouse.
Description
The granulocyte macrophage-colony-stimulating factor receptor (GM-CSF-R) is a heterodimer composed of 2 subunits, alphaand beta, and ligand binding to the high-affinity receptor leads to signalling for the multiple actions of GM-CSF on target cells. The GM-CSF receptors are found on the surface of myeloid precursors, granulocytes, mononuclear phagocyte, and also frequently present on the myeloid malignancies. The GM-CSF-R-alpha transduces a signal that results in the proliferation, differentiation, and functional activation of hematopoietic cells