AAA Biotech, LLC's RAT ANTI MOUSE CD301:RPE Antibody is a Rat monoclonal antibody. It reacts with Mouse. This antibody has been shown to work in applications such as: Flow Cytometry.
Description
Rat anti Mouse CD301 antibody, clone ER-MP23 recognizes murine CD301, a ~38 kDa cell surface protein, otherwise known as macrophage galactose N-acetylgalactosamine lectin (MGL) or dendritic cell asialoglycoprotein (DC-ASGPR).In mice, CD301 is predominantly expressed on mature macrophages found associated with a wide range of connective tissues including macrophages in the dermis and the pancreas. Clone ER-MP23 also detects a population of dendritic cells in lymphoid tissue, which are probably recent immigrants from peripheral connective tissue sites. Expression of CD301 is induced by alternative (i.e. IL-4/IL-13 mediated) activation of macrophages and dendritic cells, but not all CD301 positive cells are necessarily IL-4/IL-13 stimulated.Rat anti Mouse CD301 antibody, clone ER-MP23 is reported to block the function of mouse CD301 (Dupasquier et al. 2006). Rat anti Mouse CD301 antibody, clone ER-MP23 binds both MGL1 and MGL2 homologues