LRRK1 Antibody PA5-13868 from Thermo Fisher Scientific

Product Specs
ItemLRRK1 Antibody
CompanyThermo Fisher Scientific
Price Supplier Page
Catalog NumberPA5-13868
ApplicationsWestern Blot
ReactivityHuman, Mouse
TargetLRRK1
NCBI Gene AliasesmKIAA1790, Roco1, RIPK6, C230002E15Rik, D130026O16Rik, OSMD
Conjugate/TagUnconjugated
Quantity400 µL
FormatPBS with 0.09% sodium azide; pH 7.4
HostRabbit
ClonalityPolyclonal
NCBI Full Gene Nameleucine-rich repeat kinase 1, leucine rich repeat kinase 1
Concentration2 mg/mL
ImmunogenKLH conjugated synthetic peptide between 1981-2015 amino acids from the C-terminal region of human LRRK1
IsotypeIgG
Storage Temperature-20° C, Avoid Freeze/Thaw Cycles
PurityAmmonium sulfate precipitation, Size-exclusion - Dialysis
Antibody TypePrimary
StorageStore at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles

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(1) Preformed fibrils of α-synuclein rapidly activate LRRK2 on early endosomes, driving Rab5 phosphorylation and disrupting endolysosomal and synaptic functionnpj Parkinson's DiseaseMay 12, 2026Xinxin Zuo, Zeyu Chen, Xu-Qiao Chen, Dongxu Guan, Peter X. Shaw, Aaron Johnstone, Ann Becker, Utpal Das, William C. Mobley(phospho S1292) (Abcam; Cat# ab203181), Rabbit Polyclonal anti-LRRK1 (Thermo Fisher Scientific; Cat# PA5-13868), Rabbit Polyclonal anti-MANBA (Thermo Fisher Scientific; Cat# PA5-90351), Rabbit Polyclonal anti-mTOR

(2) Age-Dependent Dopaminergic Neurodegeneration and Impairment of the Autophagy-Lysosomal Pathway in LRRK-Deficient MiceNeuronNovember 15, 2017Giaime E, Tong Y, Wagner LK, Yuan Y, Huang G, Shen J.RESOURCE,SOURCE,IDENTIFIER Antibodies,Antibodies,Antibodies Rabbit anti-LRRK1,Thermo Fisher Scientific,Cat # PA5-13868 RRID:AB_2297136 Rabbit anti-LRRK2,"Tong et al., 2010 Shen lab",N/A Mouse anti-spectrin,Sigma-Aldrich,Cat

(3) FIH-1 disrupts an LRRK1/EGFR complex to positively regulate keratinocyte migrationThe American journal of pathologyDecember 1, 2014Peng H, Kaplan N, Yang W, Getsios S, Lavker RM.

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