FXN Antibody PA5-13411 from Thermo Fisher Scientific

Product Specs
ItemFXN Antibody
CompanyThermo Fisher Scientific
Price Supplier Page
Catalog NumberPA5-13411
ApplicationsImmunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
NCBI Gene AliasesCyaY, FA, FARR, FRDA, X25
TargetFXN
FormatPBS with 0.09% sodium azide; pH 7.4
Conjugate/TagUnconjugated
HostRabbit
ReactivityHuman
Quantity400 µL
ClonalityPolyclonal
NCBI Full Gene Namefrataxin
Concentration2 mg/mL
ImmunogenKLH conjugated synthetic peptide between 72-102 amino acids from the central region of human FXN
IsotypeIgG
Storage Temperature-20° C, Avoid Freeze/Thaw Cycles
PurityAmmonium sulfate precipitation, Size-exclusion - Dialysis
Antibody TypePrimary
StorageStore at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles

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(1) Brain microvascular endothelial cells differentiated from a Friedreich's Ataxia patient iPSC are deficient in tight junction protein expression and paracellularly permeableFront Mol NeurosciApril 15, 2025Frances M. Smith, Daniel J. Kosmanmanufacturer instructions unless otherwise noted. Antibodies Primary: Rabbit α-FXN (ThermoFisher #PA5-13411, used at 1:500), Mouse α-TATA Binding Protein (ThermoFisher #49–1,036, used at 3.2 μg/ml), Rabbit α-Nrf2

(2) Frataxin-deficient human brain microvascular endothelial cells lose polymerized actin and are paracellularly permeable –implications for blood-brain barrier integrity in Friedreich’s AtaxiabioRxivFebruary 14, 2023Frances M. Smith, Daniel J Kosmanperformed per manufacturer instructions unless otherwise stated. Antibodies Rabbit α-FXN (ThermoFisher PA5–13411), Goat α-rabbit:HRP (Cell Signaling Technologies 7074), Mouse α-TATA Binding Protein (ThermoFisher 49–1036),

(3) Loss of filamentous actin, tight junction protein expression, and paracellular barrier integrity in frataxin-deficient human brain microvascular endothelial cells-implications for blood-brain barrier physiology in Friedreich's ataxiaFrontiers in molecular biosciencesJanuary 1, 2023Smith FM, Kosman DJ.manufacturer instructions unless otherwise stated. Antibodies Primary: Rabbit α-FXN (ThermoFisher #PA5-13411, used at 1:500), Mouse α-TATA-binding protein (ThermoFisher #49-1036, used at 3.2 μg/mL), Rabbit α-Nrf2

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