MAVS Antibody PA5-17256 from Thermo Fisher Scientific

Product Specs
ItemMAVS Antibody
CompanyThermo Fisher Scientific
Price Supplier Page
Catalog NumberPA5-17256
Quantity100 µL
ReactivityHuman
TargetMAVS
NCBI Gene AliasesCARDIF, IPS-1, IPS1, VISA
Conjugate/TagUnconjugated
HostRabbit
ApplicationsImmunocytochemistry, Western Blot
Format0.01M HEPES with 100µg/mL BSA, 50% glycerol, 0.15M NaCl and no preservative; pH 7.5
ClonalityPolyclonal
NCBI Full Gene Namemitochondrial antiviral signaling protein
ImmunogenSynthetic peptide corresponding to residues at the carboxyl terminus of human MAVS
IsotypeIgG
Storage Temperature-20°C
PurityAffinity chromatography
Antibody TypePrimary
Concentration71 µg/mL
Storage-20°C

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(1) Expression of intron-containing HIV-1 RNA induces NLRP1 inflammasome activation in myeloid cellsPLoS biologySeptember 1, 2025Jalloh S, Hughes IK, Akiyama H, Gojanovich AD, Quiñones-Molina AA, Yang M, Henderson AJ, Mostoslavsky G, Gummuluru S.(Sigma, #06503-I, 1:1000), rabbit anti-CARD8 (Abcam, #ab194585, 1:1000), rabbit anti-MAVS (Invitrogen, #PA5-17256, 1:1000), rabbit anti-STING (Cell Signaling, #13647, 1:1000). Blots were washed 3 times for 5 min with

(2) 5’ cap sequestration is required for sensing of unspliced HIV-1 RNA by MDA5bioRxivAugust 29, 2025Ivy K. Hughes, Siarhei Kharytonchyk, Sita Ramaswamy, Sallieu Jalloh, James B. Hood, Xianbao He, Andrew J. Henderson, Hisashi Akiyama, Alice Telesnitsky, Suryaram Gummuluru(AdipoGen cat. # AG-20B-0009-C100, mouse monoclonal, used at 1:1000), anti-MAVS (Thermo Fisher cat. # PA5–17256, rabbit polyclonal, used at 1:1000), anti-p24Gag (NIH/NIAID HIV Reagent Program, cat. # ARP-6457, mouse

(3) The macrophage-intrinsic MDA5/IRF5 axis drives HIV-1 intron-containing RNA-induced inflammatory responsesJ Clin InvestAugust 15, 2025Sita Ramaswamy, Hisashi Akiyama, Jacob Berrigan, Andrés A. Quiñones-Molina, Alex J. Olson, Yunhan Chen, YanMei Liang, Andrew J. Henderson, Archana Asundi, Manish Sagar, et al.μg) were analyzed by Western blotting using the following antibodies: rabbit anti-MAVS (Invitrogen; PA5-17256; 1:1,000), rabbit anti-IRF3 (Cell Signaling; 4302S; 1:1,000), rabbit anti-IRF5 (Cell Signaling; 76983S;

(4) Effective recognition of double-stranded RNA does not require activation of cellular inflammationSci AdvApril 11, 2025Karolina Drazkowska, Julia Cieslicka, Michal Kitowicz, Anna Pastucha, Lukasz Markiewicz, Wiktoria Szymanek, Krzysztof Goryca, Tomasz Kowalczyk, Dominik Cysewski, Andreas R. Bausch, et al.RRID:AB_10001915), rabbit anti-IFIT1 (Invitrogen, PA3-848, RRID:AB_1958733), rabbit anti-MAVS (Invitrogen, PA5-17256, RRID:AB_10979584), rabbit anti-OAS1 (Invitrogen, PA5-82113, RRID:AB_2789274), mouse anti-OAS2 (Invitrogen,

(5) IFIH1 (MDA5) is required for innate immune detection of intron-containing RNA expressed from the HIV-1 provirusProceedings of the National Academy of Sciences of the United States of AmericaJuly 16, 2024Guney MH, Nagalekshmi K, McCauley SM, Carbone C, Aydemir O, Luban J.

(6) Long-term administration of Western diet induced metabolic syndrome in mice and causes cardiac microvascular dysfunction, cardiomyocyte mitochondrial damage, and cardiac remodeling involving caveolae and caveolin-1 expressionBiology directMarch 6, 2023Liu IF, Lin TC, Wang SC, Yen CH, Li CY, Kuo HF, Hsieh CC, Chang CY, Chang CR, Chen YH, et al.(1:100, sc-7199, Santa Cruz Biotechnology), mitochondrial antiviral-signaling protein (MAVS) (1:100, Cat #PA5-17256, Invitrogen), Mitofusin 2 (MFN2) (1:100, sc-100560, Santa Cruz), and lipid (70065-T, Biotium, Fremont,

(7) CD169-mediated restrictive SARS-CoV-2 infection of macrophages induces pro-inflammatory responsesPLoS pathogensOctober 1, 2022Jalloh S, Olejnik J, Berrigan J, Nisa A, Suder EL, Akiyama H, Lei M, Ramaswamy S, Tyagi S, Bushkin Y, et al.#AF933, 1;1000), rabbit anti-STING (Cell Signaling, #13647, 1:1000), rabbit anti-MAVS (Thermo Fisher, #PA5-17256, 1:1000), mouse anti-RIG-I (AdipoGen, #20B-0009, 1:1000), rabbit anti-MDA-5 (Proteintech, #21775-1-AP,

(8) CD169-mediated restrictive SARS-CoV-2 infection of macrophages induces pro-inflammatory responsesbioRxiv : the preprint server for biologyMarch 30, 2022Jalloh S, Olejnik J, Berrigan J, Nisa A, Suder EL, Akiyama H, Lei M, Tyagi S, Bushkin Y, Mühlberger E, et al.#AF933, 1;1000), rabbit anti-STING (Cell Signaling, #13647, 1:1000), rabbit anti-MAVS (Thermo Fisher, #PA5–17256, 1:1000), mouse anti-RIG-I (AdipoGen, #20B-0009, 1:1000), rabbit anti-MDA-5 (Proteintech, #21775–1-AP,

(9) The microRNAs miR-302b and miR-372 regulate mitochondrial metabolism via the SLC25A12 transporter, which controls MAVS-mediated antiviral innate immunityThe Journal of biological chemistryJanuary 10, 2020Yasukawa K, Kinoshita D, Yaku K, Nakagawa T, Koshiba T.

(10) HIV-1 intron-containing RNA expression induces innate immune activation and T cell dysfunctionNature communicationsAugust 27, 2018Akiyama H, Miller CM, Ettinger CR, Belkina AC, Snyder-Cappione JE, Gummuluru S.Ding, NIH AIDS Reagent Program, #4811, 1:1000), a rabbit anti-MAVS polyclonal antibody (Thermo Fisher, #PA5-17256, 1:1000), a rabbit anti-STING polyclonal antibody (Cell Signaling, #13647, 1:1000), a mouse anti-RIG-I

(11) Viral suppressors of the RIG-I-mediated interferon response are pre-packaged in influenza virionsNature communicationsDecember 9, 2014Liedmann S, Hrincius ER, Guy C, Anhlan D, Dierkes R, Carter R, Wu G, Staeheli P, Green DR, Wolff T, et al.outer mitochondrial membrane (1:1,000; Tom20; SCBT; sc-11415), RIG-I (1:500; Cell Signaling; #4520) and MAVS (1:200; Pierce; PA5-17256). Nuclear stain was performed using Hoechst 33258 (Life Technologies; H3569). Following incubation,

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MAVS Antibody

MAVS Antibody from Thermo Fisher Scientific

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MAVS Antibody from Thermo Fisher Scientific

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