Phospho-Rb (Ser608) (D10F2) Rabbit mAb 8147S from Cell Signaling Technology

Product Specs
ItemPhospho-Rb (Ser608) (D10F2) Rabbit mAb
CompanyCell Signaling Technology
Price $401.00 Inquire
Catalog Number8147S
Quantity100 µl
ApplicationsW, IP
ReactivityH
TargetRb (Ser608) phosphate
ModificationsRb (Ser608) phosphate
HostRabbit
NCBI Gene AliasesOSRC, PPP1R130, RB, p105-Rb, p110-RB1, pRb, pp110
ClonalityMonoclonal
NCBI Full Gene NameRB transcriptional corepressor 1
Research AreaCell Cycle / Checkpoint Control
IsotypeIgG
CloneD10F2
Molecular Weight110

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) Combination of low-intensity pulsed ultrasound irradiating immune organs with immune checkpoint blockade augments systemic anti-tumor immunity on low tumor burden 4T-1 breast cancerCancer Immunol ImmunotherAugust 6, 2025Jixi Li, Linqing Wen, Yujun Guo, Dan Yao, Bihang Sun, Hai Mou, Nianzhi Chen, Kun Zhou, Yan Wang, Wenzhi Chenwith a secondary antibody at 37 °C for 30 min. For mIHC, TSA working solution (Cat #: BMHC023T, Lot #: 8147-202505, Biosc biotechnology, China) was applied to enhance signal detection. Microwave treatment was

(2) Mdm2 targeting via PROteolysis TArgeting Chimeras (PROTAC) is efficient in p53 wildtype, p53-mutated, and abemaciclib-resistant estrogen receptor-positive cell lines and superior to mdm2 inhibitionBMC CancerJune 1, 2025Alina Goerg, Gerhard Piendl, Veruschka Albert, Olaf Ortmann, Anja Kathrin Wege, Gero Brockhoffp53 (Cat# 9282, RRID: AB_331476), Rb (Cat# 9309, RRID: AB_823629; 1:2000), phospho-Rb Ser608 (Cat# 8147, RRID: AB_10949974), phospho-Rb Ser780 (Cat# 8180, RRID: AB_10950972), phosho-Rb Ser795 (Cat# 9301,

(3) Functional screening reveals genetic dependencies and diverging cell cycle control in atypical teratoid rhabdoid tumorsGenome biologyDecember 2, 2024Merk DJ, Tsiami F, Hirsch S, Walter B, Haeusser LA, Maile JD, Stahl A, Jarboui MA, Lechado-Terradas A, Klose F, et al.RB-pSer807/Ser811 (Cell Signaling, 8516), RB-pSer780 (Cell Signaling, 3590), RB-pSer608 (Cell Signaling, 8147), RB-pSer795 (Cell Signaling, 9301), RBPSUH (Cell Signaling, 5313), RPA2 p34 (Millipore, 04–1481), Survivin

(4) Establishment and Characterization of Immortalized Human Dermal Papilla Cells Expressing Human Papillomavirus 16 E6/E7Journal of microbiology and biotechnologyMarch 28, 2024Kim S, Jeon KB, Park HM, Kim J, Lim CM, Yoon DY.cyclin E (#sc-481) (Santa Cruz Biotechnology, USA), p21(#2947T), CDK2 (#2546T), pRb (#9309s), and p-pRb (#8147s) (Cell Signaling Technology, USA) were used. Densitometric graphs of three independent experiments were

(5) SPOP suppresses pancreatic cancer progression by promoting the degradation of NANOGCell death & diseaseOctober 17, 2019Tan P, Xu Y, Du Y, Wu L, Guo B, Huang S, Zhu J, Li B, Lin F, Yao L.China): cyclin-dependent kinase 1 (CDK1; Catalog No. 9116S), CDK2 (2546S), Rb (9309S), pRb-Ser608 (8147S), pRb-Ser795 (9301S), E-cadherin (14472S), vimentin (5741S), matrix metalloprotease-9 (MMP9; 13667S),

(6) HIF-independent synthetic lethality between CDK4/6 inhibition and VHL loss across speciesScience signalingOctober 1, 2019Nicholson HE, Tariq Z, Housden BE, Jennings RB, Stransky LA, Perrimon N, Signoretti S, Kaelin WG Jr.(Ser795) (used at 1:5000; Cell Signaling, no. 9301), α–phospho-pRb (Ser608) (1:5000; Cell Signaling, no. 8147), ––phospho-pRb (Ser807/811) (1:5000; Cell Signaling, no. 8516), mouse α-pRb (used at 1:5000; Cell Signaling,

(7) Discovery of Covalent CDK14 Inhibitors with Pan-TAIRE Family SpecificityCell chemical biologyJune 20, 2019Ferguson FM, Doctor ZM, Ficarro SB, Browne CM, Marto JA, Johnson JL, Yaron TM, Cantley LC, Kim ND, Sim T, et al.,Cell Signaling Technologies,Cat # 3452 Rabbit monoclonal anti Phospho-RB S608,Cell Signaling Technologies,Cat # 8147 Rabbit monoclonal anti Phospho-RB S780,Cell Signaling Technologies,Cat # 8180 Rabbit polyclonal anti

(8) Engineering biofunctional in vitro vessel models using a multilayer bioprinting techniqueScientific ReportsDecember 1, 2018Jan Schöneberg, Federica De Lorenzi, Benjamin Theek, Andreas Blaeser, Dirk Rommel, Alexander J. C. Kuehne, Fabian Kießling, Horst Fischer

(9) Hyper-phosphorylation of Rb S249 together with CDK5R2/p39 overexpression are associated with impaired cell adhesion and epithelial-to-mesenchymal transition: Implications as a potential lung cancer grading and staging biomarkerPLOS ONENovember 19, 2018Jaileene Pérez-Morales et al.(Cat. No. GTX24777, Genetex, Irvine, CA); phospho-Rb (S608), rabbit monoclonal D10F2, 1:1000 (Cat. No. 8147, Cell Signaling, Danvers, MA); phospho-Rb (S780), rabbit monoclonal D59B7, 1: 1000 (Cat. No. 8180, Cell Signaling

(10) Real-Time Ligand Binding of Fluorescent VEGF-A Isoforms that Discriminate between VEGFR2 and NRP1 in Living CellsCell Chemical BiologyOctober 18, 2018Chloe J. Peach, Laura E. Kilpatrick, Rachel Friedman-Ohana, Kris Zimmerman, Matthew B. Robers, Keith V. Wood, Jeanette Woolard, Stephen J. Hill

(11) Generation of a disease-specific iPS cell line derived from a patient with Charcot-Marie-Tooth type 2K lacking functional GDAP1 geneStem cell researchJanuary 1, 2017Martí S, León M, Orellana C, Prieto J, Ponsoda X, López-García C, Vílchez JJ, Sevilla T, Torres J.

(12) SIX1 is overexpressed in endometrial carcinoma and promotes the malignant behavior of cancer cells through ERK and AKT signalingOncology lettersNovember 1, 2016Xin X, Li Y, Yang X.Millipore), phosphorylated (p)‑retinoblastoma protein (Rb) (rabbit monoclonal antibody; dilution, 1:1,000; 8147; Cell Signaling Technology, Inc., Danvers, MA, USA), p‑ERK (rabbit polyclonal antibody; dilution, 1:1,000;

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Phospho-Rb (Ser608) (D10F2) Rabbit mAb

Phospho-Rb (Ser608) (D10F2) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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Phospho-Rb (Ser608) (D10F2) Rabbit mAb from Cell Signaling Technology

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