Tie2 (D9D10) Rabbit mAb 7403S from Cell Signaling Technology

Product Specs
ItemTie2 (D9D10) Rabbit mAb
CompanyCell Signaling Technology
Price $339.00 Inquire
Catalog Number7403S
Quantity100 µl
ApplicationsW, W-S
ReactivityH
TargetTie2
HostRabbit
NCBI Gene AliasesCD202B, GLC3E, TIE-2, TIE2, VMCM, VMCM1
ClonalityMonoclonal
NCBI Full Gene NameTEK receptor tyrosine kinase
Research AreaRTK
IsotypeIgG
CloneD9D10
Molecular Weight160

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) Clioquinol inhibits angiogenesis by promoting VEGFR2 degradation and synergizes with AKT inhibition to suppress triple-negative breast cancer vascularizationAngiogenesisFebruary 3, 2025Yuan Gu, Tianci Tang, Moqin Qiu, Hongmei Wang, Emmanuel Ampofo, Michael D. Menger, Matthias W. Laschke9740; RRID: AB_11178519; Cell Signaling Technology), rabbit monoclonal anti-Tie2 antibody (1:250; Cat# 7403; RRID: AB_10949315; Cell Signaling Technology), rabbit monoclonal anti-p-FAK antibody (1:250; Cat# 8556;

(2) Sestrin2 Suppression Promotes Endothelial–Mesenchymal Transition and Exacerbates Methylglyoxal-Induced Endothelial DysfunctionInternational Journal of Molecular SciencesDecember 16, 2024Shahenda Salah Abdelsalam, Muhammad Ammar Zahid, Sarah Khalaf Ghanem, Abbas Khan, Aijaz Parray, Abdelali Agounimolecule (PECAM-1) (#77699S), tyrosine kinase with immunoglobin and EGF homology domains 2 (Tie2) (#7403S), vimentin (#5741S), transforming growth factor (TGF)-β (#3711S), GAPDH (#2118S) (Cell Signalling Technology,

(3) Cationic LNP-formulated mRNA expressing Tie2-agonist in the lung endothelium prevents pulmonary vascular leakageMolecular Therapy - Nucleic AcidsDecember 12, 2023Katrin Radloff, Birgitt Gutbier, Charlotte Maeve Dunne, Hanieh Moradian, Marko Schwestka, Manfred Gossen, Katharina Ahrens, Laura Kneller, Yadong Wang, Akanksha Moga, et al.1 (Abcam, Cambridge, UK, catalog no. ab183701), human Tie2 (Cell Signaling Technology, catalog no. 7403), mouse Tie2 (Merck, catalog no. 05–584), pY992 Tie2 (R&D Systems, Minneapolis, MN, catalog no. AF2720),

(4) A ROCK inhibitor suppresses the transforming growth factor-beta-2-induced endothelial-mesenchymal transition in Schlemm's canal endothelial cellsScientific reportsJune 14, 2023Fujimoto T, Inoue-Mochita M, Inoue T."Cell Signaling Technology, Danvers, MA",Snail,3879,1/1000 "Cell Signaling Technology, Danvers, MA",Tie2,7403,1/1000 "Cell Signaling Technology, Danvers, MA",p38,9212,1/1000 "Cell Signaling Technology, Danvers,

(5) A novel implant surface modification mode of Fe3O4-containing TiO2 nanorods with sinusoidal electromagnetic field for osteoblastogenesis and angiogenesisMaterials today. BioApril 1, 2023Ren R, Guo J, Song H, Wei Y, Luo C, Zhang Y, Chen L, Gao B, Fu J, Xiong W.(A00227-1, Boster, Wuhan, China); rabbit antibodies against VEGF 165A (ab106580, Abcam, MA, USA), Tie2 (#7403, Cell Signaling Technology, MA, USA), OPN (ab214050, Abcam, MA, USA), RUNX2 (#12556, Cell Signaling Technology

(6) VEGF Induces Expression of Genes That Either Promote or Limit Relaxation of the Retinal Endothelial BarrierInternational Journal of Molecular SciencesMarch 29, 2023Maximilian McCann, Yueru Li, Basma Baccouche, Andrius KazlauskasVEGFR2 (CST 2479S, Danvers, MA, USA), b-actin (CST 4970S), phospho-Tie2 (CST 4221S), and Tie2 (CST 7403S). Protein abundance was quantified using ImageJ (NIH, Bethesda, MD, USA). 4.5. Electric Cell-Substrate

(7) Local and Systemic Overexpression of COMP-Ang1 Induces Ang1/Tie2-Related Thrombocytopenia and SDF-1/CXCR4-Dependent AnemiaStem CellsJanuary 30, 2023Sim HJ, Bhattarai G, Kim MH, So HS, Poudel SB, Cho ES, Kook SH, Lee JC.measured using flow cytometer (BD Aria; BD Biosciences) after staining with PE-conjugated antibody (cat.#7403; Cell Signaling). To evaluate the impacts of COMP-Ang1 overexpression in Col2.3-Cre;c-Ang1 mice on BM-mesenchymal stem cells

(8) Brassinin Promotes the Degradation of Tie2 and FGFR1 in Endothelial Cells and Inhibits Triple-Negative Breast Cancer AngiogenesisCancersJuly 21, 2022Gu Y, Becker V, Qiu M, Tang T, Ampofo E, Menger MD, Laschke MW.Cell Signaling Technology; #9740), a rabbit monoclonal anti-Tie2 antibody (1:300; Cell Signaling Technology; #7403), a rabbit monoclonal anti-phosphorylated AKT (p-AKT) antibody (1:300; Cell Signaling Technology; #4060),

(9) Gatekeeping role of Nf2/Merlin in vascular tip EC induction through suppression of VEGFR2 internalizationScience advancesJune 10, 2022Bae JH, Yang MJ, Jeong SH, Kim J, Hong SP, Kim JW, Kim YH, Koh GY.monoclonal (CST, #2479), rabbit anti–VE-cadherin monoclonal (CST, #2500), rabbit anti-Tie2 monoclonal (CST, #7403), rabbit anti-VEGFR3 polyclonal (Abcam, ab27278), rabbit anti–p-NF2 (S518) polyclonal (Abcam, ab2478),

(10) Chemoproteomic profiling reveals cellular targets of nitro-fatty acidsRedox biologyOctober 1, 2021Fang MY, Huang KH, Tu WJ, Chen YT, Pan PY, Hsiao WC, Ke YY, Tsou LK, Zhang MM.anti-RXRα (#3085, 1:1000 dilution) were purchased from Cell Signaling Technology. Streptavidin-HRP (#7403, 1:5000 dilution) was from Abcam. Anti-mouse-HRP (#115-035-003, 1:20000 dilution) and anti-rabbit-HRP

(11) Inverse and reciprocal regulation of p53/p21 and Bmi-1 modulates vasculogenic differentiation of dental pulp stem cellsCell death & diseaseJune 24, 2021Zhang Z, Oh M, Sasaki JI, Nör JE.(Santa Cruz Biotechnology; Santa Cruz, CA, USA); mouse anti-GAPDH (MAB374; Millipore Sigma); rabbit anti-human Tie-2 (7403), Bmi-1(6964), PDGFR-a (5241), PDGFR-β (4564), p21 (2947) (Cell Signaling; Danvers, MA, USA); mouse

(12) Motor fatigue is associated with asymmetric connectivity properties of the corticospinal tract in multiple sclerosisNeuroImage: ClinicalAugust 25, 2020Christian Bauer, Tim B. Dyrby, Finn Sellebjerg, Kathrine Skak Madsen, Olivia Svolgaard, Morten Blinkenberg, Hartwig Roman Siebner, Kasper Winther Andersen= 25,, ,Mean,SD,95% CI,Mean,SD,95% CI,p – value, ACM values – Non-CST-NAWM,Left,7200,681,"(7026, 7403)",7072,723,"(6781, 7300)",0.280, ,Right,7218,668,"(7043, 7420)",6975,712,"(6695, 7206)",0.083, ,LI(%),−0.140,2.594,"(−1.026,

(13) Matrine inhibits the development and progression of ovarian cancer by repressing cancer associated phosphorylation signaling pathwaysCell death & diseaseOctober 10, 2019Zhang X, Hou G, Liu A, Xu H, Guan Y, Wu Y, Deng J, Cao X.phospho-VEGF Receptor 2 (Y1175) (#2478), VEGF Receptor 2 (#2479), phospho-Tie2 (Y992) (#4221), Tie2 (#7403), β-actin (#4970) and GAPDH (#5174) were purchased from Cell Signaling Technology, Inc. (Beverly, MA).

(14) Targeting promiscuous heterodimerization overcomes innate resistance to ERBB2 dimerization inhibitors in breast cancerBreast cancer research : BCRMarch 21, 2019Kennedy SP, Han JZR, Portman N, Nobis M, Hastings JF, Murphy KJ, Latham SL, Cadell AL, Miladinovic D, Marriott GR, et al.phospho-ERBB3 (#2842) total MET (#8198), total NTRK1 (#2508), phospho-NTRK1 (#4621), total TIE-2 (#7403) and pTIE-2 (#4221) and PY100 (#9411) were from Cell Signaling (MA, USA). Antibodies against phospho-METY1234,

(15) Targeting the Tie2-α_vβ₃ integrin axis with bi-specific reagents for the inhibition of angiogenesisBMC biologyAugust 17, 2018Shlamkovich T, Aharon L, Koslawsky D, Einav Y, Papo N.and 1:1000 dilution anti-Tie2-specific rabbit monoclonal antibodies (Cell Signaling Technology, Cat# 7403S, RRID:AB_10949315), 1:1000 dilution anti-phospho-Akt-specific (Cell Signaling Technology, Cat# 4060,

(16) Transcriptome Profiling of Neovascularized Corneas Reveals miR-204 as a Multi-target Biotherapy Deliverable by rAAVsMolecular therapy. Nucleic acidsMarch 2, 2018Lu Y, Tai PWL, Ai J, Gessler DJ, Su Q, Yao X, Zheng Q, Zamore PD, Xu X, Gao G.anti-VEGF (ab46154; Abcam, Cambridge, MA, USA), anti-Angpt1 (ab95230; Abcam), anti-Tie2 (catalog [Cat.] no. 7403; Cell Signaling, Danvers, MA, USA), anti-phospho-Tie2 (AF2720-SP; R&D Systems, Minneapolis, MN, USA),

(17) Flora and Threatened and Endangered Plants of Canaveral National Seashore, FloridaCastaneaJune 1, 2016Paul A. Schmalzer, Tammy E. FosterC: S&F 04-336, E (KSC: FTU238); OSP; UN Polygala rugelii Shuttlew. ex Chapm. C: S&F 04-223, E (CANA: 7403); FM; UN Polygala setacea Michx. C: S&F 02-073; OSP; UN Polygala violacea Aubl. C: S&F 02-177, 02-229,

(18) Fibulin-5 Regulates Angiopoietin-1/Tie-2 Receptor Signaling in Endothelial CellsPloS oneJanuary 1, 2016Chan W, Ismail H, Mayaki D, Sanchez V, Tiedemann K, Davis EC, Hussain SN.

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Tie2 (D9D10) Rabbit mAb

Tie2 (D9D10) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

Citations (18)

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Tie2 (D9D10) Rabbit mAb from Cell Signaling Technology

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