Nicastrin (D65G7) Rabbit mAb 9447S from Cell Signaling Technology

Product Specs
ItemNicastrin (D65G7) Rabbit mAb
CompanyCell Signaling Technology
Price $339.00 Inquire
Catalog Number9447S
Quantity100 µl
ApplicationsW, IP
ReactivityH, M, R, Mk
TargetNicastrin
HostRabbit
NCBI Gene AliasesATAG1874
ClonalityMonoclonal
NCBI Full Gene Namenicastrin
Research AreaNeuroscience
IsotypeIgG
CloneD65G7
Molecular Weight110, 120

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Cell Signaling Technology

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Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

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Website: http://www.cellsignal.com/

Website: Technical Support

(1) Poly(ADP-ribose) Polymerase 1 Deficiency Attenuates Amyloid Pathology, Neurodegeneration, and Cognitive Decline in a Familial Alzheimer’s Disease ModelbioRxivSeptember 16, 2025Aanishaa Jhaldiyal, Manisha Kumari, Trupti Tripathi, Mohammed Repon Khan, Justin Wang, Lauren Guttman, Devanik Biswas, Abhishek Pasupuleti, Akansha Aggarwal, Shraddha Pandya, et al.Source APP,14-9749-82,Thermo Fisher Scientific APP-CTF,A8717–25UL,Sigma-Aldrich Nicastrin (Rabbit mAb),9447,Cell Signaling Technology BACE1,PA1–757,Thermo Fisher Scientific "PSEN1 (D39D1, Rabbit mAb)",5643,Cell Signaling Technology

(2) Insight into prostate cancer osteolytic metastasis by RelB coordination of IL‐8 and S100A4Clinical and Translational MedicineOctober 16, 2024Wenbo Sun, Kenny Xu, Xiao Li, Peipei Qian, Fan Xu, Yanyan Zhang, Xiumei Wang, Zhi Xu, Jiaji Ding, Xinyu Xu, et al.(54653), Ikkα (2682), RelA (9609), RelB (4954), c‐Rel (4727), p105/p50 (3035), p100/p52 (4882), IL‐8 (9447), Sp1 (5931), NFATc1 (8032), Snail 1 (3879), Twist 1 (46702), vimentin (5741), E‐cadherin (3195), N‐cadherin

(3) Class II phosphatidylinositol 3-kinase-C2α is essential for Notch signaling by regulating the endocytosis of γ-secretase in endothelial cellsScientific reportsMarch 4, 2021Shimizu S, Yoshioka K, Aki S, Takuwa Y.Biological Laboratories Co., Ltd., Nagoya, Japan, 1:1000), CHC (#MA1-065, Thermo Scientific, 1:1000), Nct (#9447, Cell Signaling Technology, 1:1000), GFP (#sc-9996, Santa Cruz Biotechnology, Inc., CA, USA, 1:1000),

(4) Genetic reduction of eEF2 kinase alleviates pathophysiology in Alzheimer's disease model miceThe Journal of clinical investigationFebruary 1, 2019Beckelman BC, Yang W, Kasica NP, Zimmermann HR, Zhou X, Keene CD, Ryazanov AG, Ma T.Santa Cruz Biotechnology, catalog sc-46656), nicastrin (1:1000; Cell Signaling Technology, catalog 9447), PS1 (1:1000; Cell Signaling Technology, catalog 5643), PS2 (1:1000; Cell Signaling Technology, catalog

(5) ER-associated degradation regulates Alzheimer's amyloid pathology and memory function by modulating γ-secretase activityNature communicationsNovember 13, 2017Zhu B, Jiang L, Huang T, Zhao Y, Liu T, Zhong Y, Li X, Campos A, Pomeroy K, Masliah E, et al.(Millipore, 5232, 1:2000), human membralin (Sigma, HPA042669, 1:500), nicastrin (Cell Signaling Technology, 9447 s, 1:1000), nicastrin (Millipore, MAB5556, 1:1000), β-actin (Sigma, 5441, 1:10000), NICD (Cell Signaling Technology

(6) Regulation of the epithelial to mesenchymal transition and metastasis by Raf kinase inhibitory protein-dependent Notch1 activityOncotargetJanuary 26, 2016Hae Sook Noh et al.(Cell Signaling Technology, 9979), PEN2 (Cell Signaling Technology, 8598), Nicastrin (Cell Signaling Technology, 9447), and β-actin (Sigma-Aldrich, A5441). Proteins were visualized with the Enhanced Chemiluminescence Detection

(7) An aberrant sugar modification of BACE1 blocks its lysosomal targeting in Alzheimer's diseaseEMBO molecular medicineFebruary 1, 2015Kizuka Y, Kitazume S, Fujinawa R, Saito T, Iwata N, Saido TC, Nakano M, Yamaguchi Y, Hashimoto Y, Staufenbiel M, et al.lectin The commercially available antibodies used were as follows: rabbit anti-BACE1 (5606), anti-nicastrin (9447S), anti-GGA3 (8027), anti-rab5 (3547), anti-rab7 (9367), and anti-rab9 (5118) from Cell Signaling Technology;

(8) SIRT5 regulation of ammonia-induced autophagy and mitophagyAutophagyJanuary 1, 2015Polletta L, Vernucci E, Carnevale I, Arcangeli T, Rotili D, Palmerio S, Steegborn C, Nowak T, Schutkowski M, Pellegrini L, et al.(Cell Signaling Technology, 2627), succinyl lysine (PTM-Biolabs, PTM 419), acetylated lysine (Cell Signaling Technology, 9447), ACTB (Santa Cruz Biotechnology, sc-8432), COX4I1 (Santa Cruz Biotechnology, sc-69359). Biochemical

(9) Cyclin B2 and p53 control proper timing of centrosome separationNature cell biologyJune 1, 2014Nam HJ, van Deursen JM.GNS-11, BD); rabbit anti-cyclin B2 (1:200, SC-22776, Santa Cruz); rabb t anti-p-Cdk substrates (1:1,000, 9447, Cell Signaling Technology); mouse anti-centrin 2 (1:1,000)60; mouse or rabbit anti-γ-tubulin (1:300,

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Nicastrin (D65G7) Rabbit mAb

Nicastrin (D65G7) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

Citations (9)

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Nicastrin (D65G7) Rabbit mAb from Cell Signaling Technology

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