SQSTM1/p62 (D10E10) Rabbit mAb 7695S from Cell Signaling Technology

Product Specs
ItemSQSTM1/p62 (D10E10) Rabbit mAb
CompanyCell Signaling Technology
Price $339.00 Inquire
Catalog Number7695S
ClonalityMonoclonal
NCBI Full Gene Namesequestosome 1
ApplicationsICC, IF, IP
Research AreaAutophagy
IsotypeIgG
CloneD10E10
Molecular Weight62
ReactivityHuman (Hu)
NCBI Gene AliasesA170, DMRV, FTDALS3, NADGP, OSIL, PDB3, ZIP3, p60, p62, p62B
HostRabbit
TargetSQSTM1
Quantity100 µl

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) Ubiquitin ligase ITCH regulates life cycle of SARS-CoV-2 virusElifeMay 29, 2026Qiwang Xiang, Camille Wouters, Peixi Chang, Yu-Ning Lu, Mingming Liu, Haocheng Wang, Haley Heine, Sunning Qian, Junqin Yang, Andrew Pekosz, et al.(Santa Cruz, sc-28367); ITCH (Novus Biologicals, NB100-68142); p62 (Cell Signaling Technology, 88588S and 7695S); GM130 (Proteintech, 11308-1-AP); LAMP1 (Cell Signaling Technology, 9091S); OPTN (Cayman Chemical,

(2) Loss of SPRED3 Causes Primary Hypothyroidism and Alters Thyroidal Expression of Autophagy Regulators LC3, p62, and ATG5 in MiceInt J Mol SciAugust 7, 2025Celine Dogan, Luisa Haas, Rebecca Holzapfel, Franziska Schmitt, Denis Hepbasli, Melanie Ullrich, Michael R. Bösl, Marco Abeßer, Kai Schuh, Sina Gredyrabbit anti-LC3A/B (12741, Cell Signaling Technology; Danvers, MA, USA), monoclonal rabbit anti-p62 (7695S, Cell Signaling Technology; Danvers, MA, USA), monoclonal rabbit anti-ATG5 (12994, Cell Signaling Technology;

(3) UBE4B promotes gastric cancer proliferation and metastasis by mediating FAT4 ubiquitination and degradationCell death & diseaseJuly 23, 2025Wu K, Guo Z, Fu Y, Yang S, Pan Y, Yan R, Zhou X.follows: UBE4B (18148-1-AP, Proteintech), FAT4 (A17212, ABclonal), FAT4 (NBP1-78381, Novus), P62 (#7695, Cell Signaling), LC3 (#12741, Cell Signaling), ubiquitin (10201-1-AP, Proteintech), Ki67 (#9449, Cell Signaling

(4) Autophagy Regulates Putative Anion Transporter 1 Expression in Intestinal Epithelial CellsJ Cell Mol MedMay 2, 2025Shubha Priyamvada, Dulari Jayawardena, Arivarasu N. Anbazhagan, Anoop Kumar, Seema Saksena, Ravinder K. Gill, Alip Borthakur, Waddah A. Alrefai, Pradeep K. Dudejafrom Invitrogen (catalogue no. PHZ1235). Primary antibodies for LC3II/I (cat. no. 12741) p62 (cat. no. 7695), and ATG7 (cat. no. 8558) were procured from Cell Signalling Technology (Beverly, MA). The PAT‐1 antibody

(5) Interferon-induced PARP14-mediated ADP-ribosylation in p62 bodies requires the ubiquitin-proteasome systemThe EMBO JournalApril 7, 2025Rameez Raja, Banhi Biswas, Rachy Abraham, Yiran Wang, Che-Yuan Chang, Ivo A Hendriks, Sara C Buch-Larsen, Hongrui Liu, Xingyi Yang, Chenyao Wang, et al.21,130 × g at 4 °C for 20 min. The supernatant was incubated overnight with either SQSTM1/p62 (D10E10) (#7695, CST) or Rabbit IgG control (#3990, CST) antibodies at 4 °C, followed by incubation with Protein A/G PLUS-Agarose

(6) Effects of the pan-caspase inhibitor Q-VD-OPh on human neutrophil lifespan and functionPLoS OneJanuary 7, 2025Lisa Khuu, Alisha Pillay, Allan Prichard, Lee-Ann H. Allenanti-MnSOD (Thermo Fisher #PA1-125) or p62 using rabbit anti-SQSTM1/p62 antibodies (Cell Signaling #7695, D10E10) Primary antibodies and Alexa Fluor (AF)488- and AF647-conjugated F(ab’)2 secondary antibodies

(7) Ubiquitin Ligase ITCH Regulates Life Cycle of SARS-CoV-2 VirusbioRxivDecember 8, 2024Qiwang Xiang, Camille Wouters, Peixi Chang, Yu-Ning Lu, Mingming Liu, Haocheng Wang, Junqin Yang, Andrew Pekosz, Yanjin Zhang, Jiou Wang(Santa Cruz, sc-28367); ITCH (Novus Biologicals, NB100-68142); p62 (Cell Signaling Technology, 88588S and 7695S); GM130 (Proteintech, 11308-1-AP); LAMP1 (Cell Signaling Technology, 9091S); OPTN (Cayman Chemical,

(8) TRIM44 enhances autophagy via SQSTM1 oligomerization in response to oxidative stressScientific reportsAugust 16, 2024Wang Y, Lyu L, Vu T, McCarty N.(CST, 2972); antiphospho-mTOR (Ser2448) antibody (Millipore Sigma, 09-213) anti-SQSTM1 antibody(CST, 7695,88588); anti-phospho-SQSTM1/p62 (Ser349) (E7M1A) antibody (CST, 16177S); anti-phospho-SQSTM1/p62 (Ser403)

(9) STING guides the STX17-SNAP29-VAMP8 complex assembly to control autophagyCell InsightApril 1, 2024Xiaoyu Song, Yufeng Xi, Ming Dai, Tao Li, Shihao Du, Yuxin Zhu, Mengjie Li, Yunze Li, Siqi Liu, Xia Ding, et al.anti-LC3 antibody (Cell Signaling Technology, #4108), anti-p62 antibody (Cell Signaling Technology, #7695), anti-NDP52 antibody (Abcam, ab68588), anti-VAMP8 antibody (Cell Signaling Technology, #13060), anti-α-tubulin

(10) TRIM44 promotes autophagy through SQSTM1 oligomerization in the response to oxidative stress induced by Arsenic Trioxide in cancer cellsResearch SquareFebruary 21, 2024Nami McCarty, Yuqin Wang, Lin Lyu, Trung Vu(CST, 2972); anti-phospho-mTOR (Ser2448) antibody (Millipore Sigma, 09–213) anti-SQSTM1 antibody(CST, 7695,88588); anti-phospho-SQSTM1/p62 (Ser349) (E7M1A) antibody (CST, 16177S); anti-phospho-SQSTM1/p62 (Ser403)

(11) KPT330 promotes the sensitivity of glioblastoma to olaparib by retaining SQSTM1 in the nucleus and disrupting lysosomal functionAutophagyFebruary 1, 2024Li-Hong Wang, Sen Wei, Ye Yuan, Ming-Jun Zhong, Jiao Wang, Ze-Xuan Yan, Kai Zhou, Tao Luo, Li Liang, Xiu-Wu BianTechnology, 9718S), anti-p-CHEK1 (Cell Signaling Technology, 2348S), anti-SQSTM1 (Cell Signaling Technology, 7695S), anti-LC3 (MBL BEIJING BIOTECH CO., LTD, M152-3). After primary antibody staining, cells were washed

(12) CK1δ/ε inhibition induces ULK1-mediated autophagy in tumorigenesisTranslational OncologyFebruary 1, 2024Vivian Weiwen Xue, Shanshan Liu, Qi Sun, Jiong Ning, Huan Li, Weilan Wang, Sapna Sayed, Xibao Zhao, Li Fu, Desheng Lu[Proteintech, #60004–1-Ig], CK1δ [Santa Cruz Biotechnology, #sc-55553], CK1ε [CST, #12448], SQSTM1/p62 [CST, #7695], LC3A/B [CST, #12741], ULK1 [CST, #8054], and membranes were then incubated with HRP-conjugated secondary

(13) Vacuole Membrane Protein 1 (VMP1) Restricts NLRP3 Inflammasome Activation by Modulating SERCA Activity and AutophagyResearch squareJanuary 27, 2023Zack SR, Nikolaienko R, Cook B, Melki R, Zima AV, Campbell EM.66009–1-Ig), rabbit anti-LC3B (1:1000; Sigma-Aldrich, L7543), and rabbit anti-p62 (1:500; Cell Signaling, 7695S). The nitrocellulose membrane was washed in Tri–buffered saline, 0.1% Tween 20 and probed with horseradish

(14) Kaposi’s sarcoma-associated herpesvirus (KSHV) utilizes the NDP52/CALCOCO2 selective autophagy receptor to disassemble processing bodiesPLOS PathogensJanuary 12, 2023Carolyn-Ann Robinson, Gillian K. Singh, Mariel Kleer, Thalia Katsademas, Elizabeth L. Castle, Bre Q. Boudreau, Jennifer A. CorcoranGanem,ImmunofluorescenceImmunoblot,1:10001:1000 NDP52,Rabbit,CST 60732,Immunoblot,1:1000 p62,Rabbit,CST 7695,Immunoblot,1:1000 Dcp1a,Mouse,CST 15365,Immunoblot,1:500 DDX6,Rabbit,Bethyl A300-461,Immunoblot,1:1000 Pat1b,Rabbit,CST

(15) Autolysosomal activation combined with lysosomal destabilization efficiently targets myeloid leukemia cells for cell deathFrontiers in oncologyJanuary 1, 2023Shah H, Stankov M, Panayotova-Dimitrova D, Yazdi A, Budida R, Klusmann JH, Behrens GMN.,Cell Signaling,USA Atg7,8558s,Cell Signaling,USA Lamp-1,ab25630,Abcam,UK Lamp-2,sc-18822,Santa Cruz Biotechnology,USA p62/SQSTM1,7695s,Cell Signaling,USA p4E-BP1,2855s,Cell Signaling,USA List of antibodies used in experiments.

(16) The integrated stress response remodels the microtubule-organizing center to clear unfolded proteins following proteotoxic stresseLifeJune 27, 2022Hurwitz B, Guzzi N, Gola A, Fiore VF, Sendoel A, Nikolova M, Barrows D, Carroll TS, Pasolli HA, Fuchs E.Technologies, 3195); 1/500 vinculin (MilliporeSigma, V9131); 1/250 p62/SQSTM (Cell Signaling Technologies, 7695); 1/500 α-tubulin (BD Biosciences, MCA77G); 1/500 γ-tubulin (MilliporeSigma, T6557); 1/250 pericentrin

(17) Esomeprazole inhibits hypoxia/endothelial dysfunction–induced autophagy in preeclampsiaCell and Tissue ResearchApril 1, 2022Shengyi Gu, Chenchen Zhou, Jindan Pei, Yuelin Wu, Sheng Wan, Xiaobo Zhao, Junhao Hu, Xiaolin Hua1:1000]), phospho-mTOR (5536, rabbit [WB 1:1000]), p53 (2527, rabbit [WB 1:1000] [IF 1:100]), SQSTM1/p62 (7695, rabbit [WB 1:1000] [IF 1:100]), LC3B (3868, rabbit [WB 1:1000] [IF 1:100]), and PI3 kinase class III

(18) CCDC88A/GIV promotes HBV replication and progeny secretion via enhancing endosomal trafficking and blocking autophagic degradationAutophagyFebruary 1, 2022Xueyu Wang et al.Antibody,"Cell Signaling Technology, 88588" Anti-SQSTM1 Rabbit Antibody,"Cell Signaling Technology, 7695" Anti-RAB5 Mouse Antibody,"Cell Signaling Technology, 46449" Anti-RAB5 Rabbit Antibody,"Cell Signaling Technology

(19) Single-domain antibody screening by isPLA-seqLife Science AllianceJanuary 1, 2022Yueyuan Yin, Fei Yan, Ruimin Zhou, Mingchen Li, Jinyi Ma, Zhe Liu, Zhenyi Maanti-Flag M2 affinity beads (A2220; Sigma-Aldrich), and anti-SQSTM1/p62 (ab56416, mouse monoclonal; Abcam; #7695, rabbit polyclonal; Cell Signaling Technology, respectively) were used in this study. pEASY-Basic Seamless Cloning

(20) MTORC1 inhibition drives crinophagic degradation of glucagonMolecular MetabolismNovember 1, 2021Sangam Rajak, Sherwin Xie, Archana Tewari, Sana Raza, Yajun Wu, Boon-Huat Bay, Paul M. Yen, Rohit A. Sinha(Cell Signaling Technology, #2775), anti-glucagon (Sigma–Aldrich, #G2654), anti-SQSTM1/p62 (Cell Signaling Technology, #7695), anti-GABARAP (Cell Signaling Technology, #13733), and anti-LAMP1 (DSHB, 1D4B). Colocalization studies

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SQSTM1/p62 (D10E10) Rabbit mAb (IF Preferred)

SQSTM1/p62 (D10E10) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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SQSTM1/p62 (D10E10) Rabbit mAb from Cell Signaling Technology

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