Fig 1: The effects of SIRT2 on cytoskeletal reorganization and energy metabolism in chondrocytes via the NF‐κB/NLRP3 axis. (A, B) Immunofluorescence staining showing the distribution of F‐actin and β‐tubulin in chondrocytes from each group. (C, D) WB analysis of cartilage repair‐related proteins, including COL2A1, aggrecan, and matrix‐degrading enzymes matrix metalloproteinase 9 and MMP13, across different groups. (E) ATP levels in chondrocytes from each group. (F) Electron microscopy images displaying the number and morphology of mitochondria in chondrocytes from each group. *Data are presented as mean ± standard error of the mean with *p < 0.05, **p < 0.01, and ***p < 0.001. NF‐κB, nuclear factor kappa B; NLRP3, NOD‐like receptor protein 3; SIRT2, sirtuin 2.