Fig 1: Immunoblotting analyses of LOTUS, NgR1, and MAIs in the lumbar spinal cords of WT, SOD1 Tg, and LOTUS Tg/SOD1 Tg mice.a Immunoblots of LOTUS at 20 weeks. HA-LOTUS, overexpressed hemagglutinin-tagged LOTUS; LOTUS, endogenous LOTUS. b Quantitative data of (a) at 12, 16, 20, and 24 weeks. c Immunoblots of NgR1 at 20 weeks. d Quantitative data of (c) at 12, 16, 20, and 24 weeks. e Immunoblots of Nogo-A at 20 weeks. f Quantitative data of (e) at 12, 16, 20, and 24 weeks. g Immunoblots of MAG at 20 weeks. h Quantitative data of (g) at 12, 16, 20, and 24 weeks. i Immunoblots of OMgp at 20 weeks. j Quantitative data of (i) at 12, 16, 20, and 24 weeks. Values are means ± SD (WT: n = 5; SOD1 Tg: n = 4 (12 weeks) or 5 (16, 20, and 24 weeks); LOTUS Tg/ SOD1 Tg: n = 5 (16 weeks) or 6 (12, 20, and 24 weeks)). *, p < 0.05; ****, p < 0.0001 (one-way ANOVA followed by post hoc Tukey’s test).