Fig 1: SMOX inhibition mediates the protective effects of HET-B. A Representative fluorescence images of ROS in HUVECs. B Quantitative analysis of ROS mean fluorescence intensity. C Representative images of tube formation. D Quantitative analysis of tube formation. E Western blot analysis of Nrf2 and p-NF-κB protein expression. F Densitometric quantification of Nrf2 protein levels. G Densitometric quantification of p-NF-κB protein levels. H Representative fluorescence images of ROS in HUVECs. I Quantitative analysis of ROS mean fluorescence intensity. J Representative images of tube formation. K Quantitative analysis of tube formation. L Western blot analysis of Nrf2 and p-NF-κB protein expression. M Densitometric quantification of Nrf2 protein levels. N Densitometric quantification of p-NF-κB protein levels. Scale bar = 50 μm. #P < 0.05, ##P < 0.01 versus NG; *P < 0.05, **P < 0.01 versus HG; &P < 0.05, &&P < 0.01 versus HG + HET-B