Fig 1: (A) Western blot analysis detecting Upf2 and β-Actin in the liver of WT or Upf2 Hep-KO mice. (B) qPCR detecting the relative expression of genes indicated (n = 4 for WT and n = 2 for Upf2 Hep-KO). Data shown as the mean ± SEM, * p < 0.05. (C) Western blot analysis detecting phospho-Upf1 (Ser1127) or β-Actin in mice fed with chow or GAN diet for 3 or 6 months. Each lane represents samples pooled from 5 to 7 mice.