The T-Complex Protein 1 alpha (TCP-1a, CCT) Antibody from MyBioSource.com is a Rat Monoclonal antibody. This antibody recognizes Human, Mouse, Rat, Bovine, Canine, Drosophila/Arthropod, Guinea Pig, Hamster, Non-Human Primate, Porcine, and Rabbit antigen. The T-Complex Protein 1 alpha (TCP-1a, CCT) Antibody has been shown to work in the following applications: Immunocytochemistry, Immunoprecipitation, and Western Blot.
Description
TCP-1alpha is a 60kD subunit of a cytosolic hetero-oligomer chaperone (1,4) that is known to be involved in the folding of actin and tubulin. This protein is a member of the chaperonin family, which includes Escherichia coli GroEL, the mitochondrial heat-shock protein Hsp60, the plastid Rubisco-subunit-binding protein and the archaebacterial protein TF55. These chaperonins assist the folding of proteins upon ATP hydrolysis. Nine different subunits of TCP-1 containing chaperonin complexes from mammalian testis and seven different subunits of mouse F9 cells have been identified. TCP-1 has also been referred to as ëTRicí, TCP-1 ring complex or the chaperonin containing complex, CCT